| Round | Overall | Player |
|---|---|---|
| 1 | 8th | 3B Rafael Devers Bos |
| 2 | 17th | OF Kyle Tucker Hou |
| 3 | 32nd | SP Corbin Burnes Mil |
| 4 | 41st | OF Teoscar Hernández Tor |
| 5 | 56th | SP Max Fried Atl |
| 6 | 65th | SS Carlos Correa SF |
| 7 | 80th | SP Logan Webb SF |
| 8 | 89th | 2B Jonathan India Cin |
| 9 | 104th | 1B Bobby Dalbec Bos |
| 10 | 113th | SP Kevin Gausman Tor |
| 11 | 128th | SP Aaron Civale Cle |
| 12 | 137th | OF Jarred Kelenic Sea |
| 13 | 152nd | SP Hyun-Jin Ryu Tor |
| 14 | 161st | C Gary Sanchez Min |
| 15 | 176th | 1B Miguel Sano Min |
| 16 | 185th | 2B Brendan Rodgers Col |
| 17 | 200th | OF Trent Grisham SD |
| 18 | 209th | 3B Ke'Bryan Hayes Pit |
| 19 | 224th | SP Joe Ryan Min |
| 20 | 233rd | SP Shane Baz TB |
| 21 | 248th | SP Dakota Hudson StL |
| 22 | 257th | C Keibert Ruiz Was |
| 23 | 272nd | SP Jonathan Gray Tex |
| 24 | 281st | OF Austin Hays Bal |
| 25 | 296th | RP Tanner Rainey Was |
| 26 | 305th | RP Cole Sulser Mia |
| 27 | 320th | SS C.J. Abrams Was |
| 28 | 329th | 1B Triston Casas Bos |
| 29 | 344th | RP Luis Cessa Cin |