| Round | Overall | Player |
|---|---|---|
| 1 | 1st | DH Shohei Ohtani LAA |
| 2 | 24th | 3B Manny Machado SD |
| 3 | 25th | C Salvador Perez KC |
| 4 | 48th | OF Teoscar Hernández Tor |
| 5 | 49th | SP Zach Wheeler Phi |
| 6 | 72nd | RP Craig Kimbrel LAD |
| 7 | 73rd | RP Jordan Romano Tor |
| 8 | 96th | SS Tim Anderson ChA |
| 9 | 97th | SP Frankie Montas NYA |
| 10 | 120th | OF Randy Arozarena TB |
| 11 | 121st | 1B C.J. Cron Col |
| 12 | 144th | 2B Brendan Rodgers Col |
| 13 | 145th | SP Shane McClanahan TB |
| 14 | 168th | OF Alex Kirilloff Min |
| 15 | 169th | SP Patrick Sandoval LAA |
| 16 | 192nd | 1B Luke Voit SD |
| 17 | 193rd | OF Josh Lowe TB |
| 18 | 216th | C Alejandro Kirk Tor |
| 19 | 217th | OF Ian Happ ChN |
| 20 | 240th | SP Alex Wood SF |
| 21 | 241st | SP Chris Sale Bos |
| 22 | 264th | 3B Luis Urias Mil |
| 23 | 265th | SP Jordan Montgomery NYA |
| 24 | 288th | 2B Kolten Wong Mil |
| 25 | 289th | SP John Means Bal |
| 26 | 312th | SP Nestor Cortes Jr. NYA |
| 27 | 313th | RP Art Warren Cin |
| 28 | 336th | 3B Jeff McNeil NYN |
| 29 | 337th | 1B Dom Smith NYN |