| Pos. | Starters | Team | Opp. | Status |
| QB | Jared Goff |
|
@
|
|
| RB | Josh Jacobs |
|
@
|
Questionable |
| RB | Jahmyr Gibbs |
|
@
|
|
| WR | Keenan Allen |
|
@
|
|
| WR | Zay Flowers |
|
@
|
|
| WR | Rashee Rice |
|
|
|
| TE | Albert Okwuegbunam |
|
@
|
|
| HB (RB) | Quinshon Judkins |
|
@
|
|
| PK | Will Reichard |
|
@
|
|
| DL | Dallas Turner |
|
@
|
|
| DL | Byron Murphy II |
|
|
|
| DL | Aidan Hutchinson |
|
@
|
|
| LB | Bobby Okereke |
|
|
|
| LB | Dre Greenlaw |
|
|
|
| LB | Zack Baun |
|
|
|
| CB | DaRon Bland |
|
|
|
| S | Xavier McKinney |
|
@
|
|
| Pos. | 1st Backup | Team | Opp. | Status |
| QB | Brock Purdy |
|
|
|
| RB | RJ Harvey |
|
|
|
| WR | Sterling Shepard |
|
|
|
| TE | Jonnu Smith |
|
|
|
| HB (WR) | Alec Pierce |
|
@
|
|
| PK | Jake Elliott |
|
|
|
| DL | K'Lavon Chaisson |
|
|
|
| LB | Logan Wilson |
|
|
|
| CB | Jamel Dean |
|
|
|
| S | Brian Branch |
|
@
|
Out |
| Pos. | 2nd Backup | Team | Opp. | Status |
| QB | Mac Jones |
|
|
|
| DL | T'Vondre Sweat |
|
@
|
|
| LB | Christian Rozeboom |
|
@
|
|
| CB | Tarheeb Still |
|
@
|
|
| Pos. | Bench | Team | Opp. | Status |
| TE | Zach Ertz |
|
@
|
NFI |
| TE | Tyler Higbee |
|
|
NFI |