| Pos. | Starters | Team | Opp. | Status |
| QB | Caleb Williams |
|
|
|
| RB | Bucky Irving |
|
|
|
| RB | Saquon Barkley |
|
|
|
| WR | Deebo Samuel |
|
@
|
Questionable |
| WR | Terry McLaurin |
|
@
|
|
| WR | Jayden Higgins |
|
|
|
| TE | Harold Fannin Jr. |
|
@
|
|
| HB (RB) | Bhayshul Tuten |
|
|
|
| PK | Jake Bates |
|
@
|
|
| DL | Laiatu Latu |
|
@
|
|
| DL | Khalil Mack |
|
@
|
|
| DL | Zach Allen |
|
|
|
| LB | Divine Deablo |
|
@
|
|
| LB | Daiyan Henley |
|
@
|
|
| LB | Barrett Carter |
|
|
|
| CB | Denzel Burke |
|
@
|
|
| S | Jordan Battle |
|
|
|
| Pos. | 1st Backup | Team | Opp. | Status |
| RB | Sean Tucker |
|
|
|
| WR | Andrei Iosivas |
|
|
|
| HB (RB) | Dylan Sampson |
|
@
|
Out |
| DL | Uchenna Nwosu |
|
|
|
| LB | Teddye Buchanan |
|
@
|
|
| Pos. | 2nd Backup | Team | Opp. | Status |
| WR | Cedric Tillman |
|
@
|
Questionable |
| Pos. | Bench | Team | Opp. | Status |
| QB | Drake Maye |
|
|
|
| RB | Tank Bigsby |
|
|
|
| RB | Isaac Guerendo |
|
|
|
| RB | Omarion Hampton |
|
@
|
|
| RB | Will Shipley |
|
|
|
| WR | Marvin Harrison Jr. |
|
@
|
Out |
| WR | Tetairoa McMillan |
|
@
|
|
| WR | Jaylin Noel |
|
|
|
| WR | Darius Slayton |
|
|
|
| S | Dane Belton |
|
|