| Pos. | Starters | Team | Opp. | Status |
| QB | Josh Allen |
|
@
|
|
| RB | Travis Etienne |
|
|
|
| RB | Kyle Monangai |
|
|
|
| WR | Ladd McConkey |
|
@
|
|
| WR | D.K. Metcalf |
|
|
|
| WR | Michael Pittman |
|
@
|
|
| TE | Jake Ferguson |
|
|
Questionable |
| HB (WR) | Courtland Sutton |
|
|
|
| PK | Jason Myers |
|
|
|
| DL | Danielle Hunter |
|
|
|
| DL | Jonathon Cooper |
|
|
|
| DL | Will McDonald |
|
@
|
|
| LB | Bobby Wagner |
|
@
|
|
| LB | Patrick Queen |
|
|
|
| LB | Drake Thomas |
|
|
|
| CB | Nahshon Wright |
|
|
|
| S | Jessie Bates |
|
@
|
|
| Pos. | 1st Backup | Team | Opp. | Status |
| QB | Sam Darnold |
|
|
|
| DL | Jalyx Hunt |
|
|
|
| LB | Teddye Buchanan |
|
@
|
|
| S | Reed Blankenship |
|
|
|
| Pos. | Bench | Team | Opp. | Status |
| RB | Malik Davis |
|
|
|
| RB | Emari Demercado |
|
@
|
Questionable |
| RB | Rico Dowdle |
|
@
|
|
| RB | Alvin Kamara |
|
|
Out |
| RB | Keaton Mitchell |
|
@
|
|
| RB | Samaje Perine |
|
|
|
| RB | Emanuel Wilson |
|
@
|
|
| WR | Jordan Addison |
|
@
|
|
| WR | Matthew Golden |
|
@
|
|
| WR | Quentin Johnston |
|
@
|
Questionable |
| WR | Deebo Samuel |
|
@
|
Questionable |
| TE | Juwan Johnson |
|
|