| Pos. | Bench | Team | Opp. | Status |
| QB | Sam Darnold | Sea | Bye | |
| QB | Jordan Love | GB | Bye | |
| QB | Drake Maye | NE | Bye | |
| RB | Braelon Allen | NYJ | Bye | |
| RB | Saquon Barkley | Phi | Bye | |
| RB | Ray Davis | Buf | Bye | |
| RB | Rico Dowdle | Car | Bye | |
| RB | Sincere McCormick | LV | Bye | |
| RB | Tyrone Tracy Jr. | NYG | Bye | |
| RB | Kenneth Walker | Sea | Bye | Questionable |
| RB | Breece Hall | NYJ | Bye | |
| WR | Calvin Austin | Pit | Bye | |
| WR | Keon Coleman | Buf | Bye | |
| WR | Tank Dell | Hou | Bye | Questionable |
| WR | Jerry Jeudy | Cle | Bye | |
| WR | Jameson Williams | Det | Bye | |
| WR | Nico Collins | Hou | Bye | |
| WR | Puka Nacua | LAR | Bye | |
| TE | Brock Bowers | LV | Bye | |
| TE | Isaiah Likely | Bal | Bye | |
| TE | Kyle Pitts | Atl | Bye | |
| PK | Brandon Aubrey | Dal | Bye | Questionable |
| DL | Jeffery Simmons | Ten | Bye | |
| DL | D.J. Wonnum | Car | Bye | |
| DL | Nik Bonitto | Den | Bye | |
| LB | Akeem Davis-Gaither | Cin | Bye | |
| LB | Patrick Queen | Pit | Bye | |
| LB | E.J. Speed | Ind | Bye | |
| LB | Terrel Bernard | Buf | Bye | |
| LB | Jack Campbell | Det | Bye | |
| CB | Devon Witherspoon | Sea | Bye | |
| S | Budda Baker | Ari | Bye | |
| S | Dane Belton | NYG | Bye |