| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Drake Maye | QB | NE | 22 | **** | ||
| Jameis Winston | QB | NYG | 31 | **** | ||
| Lamar Jackson | QB | Bal | 28 | **** | ||
| Tony Pollard | RB | Ten | 28 | **** | ||
| Audric Estime | RB | Den | 21 | **** | ||
| Patrick Taylor | RB | SF | 27 | **** | ||
| Isiah Pacheco | RB | KC | 26 | **** | ||
| Kendre Miller | RB | NO | 22 | **** | Questionable | Concussion |
| De'Von Achane | RB | Mia | 23 | **** | ||
| Jaleel McLaughlin | RB | Den | 24 | **** | ||
| D.K. Metcalf | WR | Pit | 27 | **** | ||
| Tank Dell | WR | Hou | 25 | **** | Questionable | Knee - ACL + MCL |
| Ja'Lynn Polk | WR | NE | 23 | **** | Questionable | Shoulder |
| Rome Odunze | WR | Chi | 22 | **** | ||
| Darius Slayton | WR | NYG | 28 | **** | ||
| Justin Jefferson | WR | Min | 26 | **** | ||
| Marquez Valdes-Scantling | WR | Sea | 30 | **** | ||
| Travis Kelce | TE | KC | 35 | **** | ||
| Pat Freiermuth | TE | Pit | 26 | **** | ||
| Jason Sanders | PK | Mia | 29 | **** | ||
| Chris Jones | DL | KC | 30 | **** | ||
| Will Anderson | DL | Hou | 23 | **** | ||
| Alex Highsmith | DL | Pit | 27 | **** | ||
| Calais Campbell | DL | Mia | 38 | **** | ||
| Akeem Davis-Gaither | LB | Cin | N/A | **** | ||
| Ernest Jones | LB | Sea | 25 | **** | Questionable | Knee |
| Quay Walker | LB | GB | 24 | **** | ||
| Marist Liufau | LB | Dal | 24 | **** | ||
| Trevin Wallace | LB | Car | 22 | **** | Questionable | Shoulder |
| Azeez Al-Shaair | LB | Hou | 27 | **** | Questionable | Knee |
| Byron Murphy | CB | Min | 27 | **** | ||
| Brandon Jones | S | Den | 27 | **** | ||
| Xavier Woods | S | Car | 29 | **** |