| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jayden Daniels | QB | Was | 24 | **** | ||
| Anthony Richardson | QB | Ind | 22 | **** | Questionable | Back |
| Tank Bigsby | RB | Jac | 23 | **** | ||
| Kyren Williams | RB | LAR | 24 | **** | ||
| D'Andre Swift | RB | Chi | 26 | **** | ||
| Alvin Kamara | RB | NO | 29 | **** | Questionable | Groin |
| Alexander Mattison | RB | Mia | 26 | **** | ||
| Brandon Aiyuk | WR | SF | 27 | **** | Questionable | Knee - ACL + MCL |
| Diontae Johnson | WR | Hou | 28 | **** | ||
| Terry McLaurin | WR | Was | 28 | **** | ||
| Jauan Jennings | WR | SF | N/A | **** | ||
| Xavier Legette | WR | Car | 24 | **** | Questionable | Foot |
| Drake London | WR | Atl | 24 | **** | ||
| Christian Watson | WR | GB | 25 | **** | Questionable | Knee - ACL |
| Cole Kmet | TE | Chi | 26 | **** | ||
| Tucker Kraft | TE | GB | N/A | **** | ||
| George Kittle | TE | SF | 31 | **** | ||
| Jake Elliott | PK | Phi | 30 | **** | ||
| Blake Grupe | PK | NO | 26 | **** | ||
| Darrell Taylor | DL | Chi | 28 | **** | ||
| Jonathon Cooper | DL | Den | 27 | **** | ||
| Aidan Hutchinson | DL | Det | 24 | **** | Questionable | Lower leg |
| Josh Hines-Allen | DL | Jac | 27 | **** | ||
| Rashan Gary | DL | GB | 27 | **** | ||
| Kwity Paye | DL | Ind | 26 | **** | ||
| K.J. Britt | LB | TB | 25 | **** | ||
| Cody Barton | LB | Den | 28 | **** | ||
| Jordyn Brooks | LB | Mia | 27 | **** | Questionable | Wrist |
| Terrel Bernard | LB | Buf | 25 | **** | ||
| DeMarvion Overshown | LB | Dal | 24 | **** | Questionable | Knee - ACL + MCL |
| Zyon McCollum | CB | TB | N/A | **** | ||
| Shemar Jean-Charles | CB | NO | N/A | **** | ||
| Jessie Bates | S | Atl | 28 | **** |