| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| J.J. McCarthy | QB | Min | 22 | **** | ||
| Bo Nix | QB | Den | 25 | **** | ||
| Sam Darnold | QB | Sea | 27 | **** | ||
| Jordan Love | QB | GB | 26 | **** | ||
| J.K. Dobbins | RB | LAC | 26 | **** | ||
| Rico Dowdle | RB | Car | 26 | **** | ||
| Braelon Allen | RB | NYJ | 21 | **** | ||
| Najee Harris | RB | LAC | 27 | **** | ||
| Kenneth Walker | RB | Sea | 24 | **** | Questionable | Ankle |
| Tyjae Spears | RB | Ten | 23 | **** | Questionable | Concussion |
| Puka Nacua | WR | LAR | 23 | **** | ||
| Parker Washington | WR | Jac | 23 | **** | ||
| Rashod Bateman | WR | Bal | 25 | **** | ||
| Nico Collins | WR | Hou | 26 | **** | ||
| Ladd McConkey | WR | LAC | 23 | **** | ||
| Troy Franklin | WR | Den | 22 | **** | ||
| Keon Coleman | WR | Buf | 21 | **** | ||
| Kyle Pitts | TE | Atl | 24 | **** | ||
| Trey McBride | TE | Ari | 25 | **** | ||
| Isaiah Likely | TE | Bal | 25 | **** | ||
| Dalton Kincaid | TE | Buf | 26 | **** | ||
| Brenton Strange | TE | Jac | N/A | **** | ||
| Brandon Aubrey | PK | Dal | 30 | **** | Questionable | Shoulder |
| Nik Bonitto | DL | Den | 25 | **** | ||
| Will McDonald | DL | NYJ | N/A | **** | ||
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| Leonard Williams | DL | Sea | 30 | **** | ||
| Tremaine Edmunds | LB | Chi | 27 | **** | ||
| Dre Greenlaw | LB | Den | 27 | **** | Questionable | Quadriceps |
| Patrick Queen | LB | Pit | 25 | **** | ||
| Jack Campbell | LB | Det | 24 | **** | ||
| Cam Taylor-Britt | CB | Cin | 25 | **** | ||
| Ugo Amadi | S | NO | N/A | **** |