| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Patrick Mahomes | QB | KC | 29 | **** | ||
| Joe Burrow | QB | Cin | 28 | **** | ||
| Kenneth Walker | RB | Sea | 24 | **** | Questionable | Ankle |
| Kyren Williams | RB | LAR | 24 | **** | ||
| Zach Charbonnet | RB | Sea | 24 | **** | ||
| Tyjae Spears | RB | Ten | 23 | **** | Questionable | Concussion |
| Blake Corum | RB | LAR | 24 | **** | Questionable | Forearm |
| Devin Singletary | RB | NYG | 27 | **** | ||
| Courtland Sutton | WR | Den | 29 | **** | ||
| Brian Thomas Jr. | WR | Jac | 22 | **** | ||
| Jaxon Smith-Njigba | WR | Sea | 23 | **** | ||
| Calvin Austin | WR | Pit | 26 | **** | ||
| Darius Slayton | WR | NYG | 28 | **** | ||
| Jerry Jeudy | WR | Cle | 26 | **** | ||
| Ja'Marr Chase | WR | Cin | 25 | **** | ||
| Dallas Goedert | TE | Phi | 30 | **** | ||
| Hunter Henry | TE | NE | 30 | **** | Questionable | Foot |
| Jason Myers | PK | Sea | 33 | **** | ||
| Joey Bosa | DL | Buf | 29 | **** | ||
| Derek Barnett | DL | Hou | 28 | **** | ||
| T.J. Watt | DL | Pit | 30 | **** | ||
| Arden Key | DL | Ten | N/A | **** | Questionable | Hand |
| Zaven Collins | DL | Ari | 25 | **** | ||
| Tuli Tuipulotu | DL | LAC | 22 | **** | ||
| Dorian Williams | LB | Buf | 23 | **** | ||
| Ventrell Miller | LB | Jac | N/A | **** | ||
| Quay Walker | LB | GB | 24 | **** | ||
| Mack Wilson | LB | Ari | 27 | **** | ||
| Tremaine Edmunds | LB | Chi | 27 | **** | ||
| Tarheeb Still | CB | LAC | 22 | **** | ||
| Taron Johnson | CB | Buf | 28 | **** | ||
| Julian Love | S | Sea | 27 | **** | ||
| Jevon Holland | S | NYG | 25 | **** |