| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Cooper Rush | QB | Dal | N/A | **** | ||
| Justin Herbert | QB | LAC | 27 | **** | ||
| Jordan Love | QB | GB | 26 | **** | ||
| Jonathan Taylor | RB | Ind | 26 | **** | ||
| Rico Dowdle | RB | Car | 26 | **** | ||
| Ray Davis | RB | Buf | 25 | **** | ||
| Tyrone Tracy Jr. | RB | NYG | 25 | **** | ||
| Braelon Allen | RB | NYJ | 21 | **** | ||
| Rhamondre Stevenson | RB | NE | 27 | **** | ||
| James Cook | RB | Buf | 25 | **** | ||
| Chase Brown | RB | Cin | 25 | **** | Questionable | Ankle |
| Puka Nacua | WR | LAR | 23 | **** | ||
| Jordan Addison | WR | Min | 23 | **** | ||
| Keon Coleman | WR | Buf | 21 | **** | ||
| Justin Jefferson | WR | Min | 26 | **** | ||
| Kyle Pitts | TE | Atl | 24 | **** | ||
| Brenton Strange | TE | Jac | N/A | **** | ||
| Trey McBride | TE | Ari | 25 | **** | ||
| Brandon Aubrey | PK | Dal | 30 | **** | Questionable | Shoulder |
| Nik Bonitto | DL | Den | 25 | **** | ||
| Greg Rousseau | DL | Buf | 25 | **** | ||
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| Chop Robinson | DL | Mia | 22 | **** | ||
| E.J. Speed | LB | Ind | 29 | **** | ||
| Eric Kendricks | LB | Dal | 33 | **** | ||
| Akeem Davis-Gaither | LB | Cin | N/A | **** | ||
| Patrick Queen | LB | Pit | 25 | **** | ||
| Christian Harris | LB | Hou | N/A | **** | ||
| Devin Lloyd | LB | Jac | 26 | **** | ||
| Deommodore Lenoir | CB | SF | 25 | **** | Questionable | Shoulder |
| Coby Bryant | CB | Sea | N/A | **** | ||
| Cooper DeJean | CB | Phi | 22 | **** | ||
| Kyle Hamilton | S | Bal | 24 | **** |