| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Patrick Mahomes | QB | KC | 29 | **** | ||
| Cooper Rush | QB | Dal | N/A | **** | ||
| Nick Chubb | RB | Cle | 29 | **** | ||
| Cam Akers | RB | Min | 25 | **** | ||
| MarShawn Lloyd | RB | GB | 24 | **** | Questionable | Hamstring |
| Isaiah Davis | RB | NYJ | 23 | **** | ||
| Najee Harris | RB | LAC | 27 | **** | ||
| Michael Carter | RB | Ari | 25 | **** | ||
| Elijah Mitchell | RB | KC | 27 | **** | ||
| Khalil Herbert | RB | Ind | 27 | **** | ||
| Dameon Pierce | RB | Hou | 25 | **** | ||
| Jaylen Warren | RB | Pit | 26 | **** | ||
| Sean Tucker | RB | TB | N/A | **** | ||
| Ja'Marr Chase | WR | Cin | 25 | **** | ||
| Christian Watson | WR | GB | 25 | **** | Questionable | Knee - ACL |
| Alec Pierce | WR | Ind | 25 | **** | ||
| DeAndre Hopkins | WR | Bal | 32 | **** | ||
| Amari Cooper | WR | Buf | 30 | **** | ||
| Malik Nabers | WR | NYG | 21 | **** | ||
| D.J. Moore | WR | Chi | 28 | **** | ||
| Will Dissly | TE | LAC | 28 | **** | ||
| Sam LaPorta | TE | Det | 24 | **** | ||
| Will Reichard | PK | Min | 24 | **** | ||
| Chop Robinson | DL | Mia | 22 | **** | ||
| Carl Granderson | DL | NO | 28 | **** | ||
| Trey Hendrickson | DL | Cin | 30 | **** | ||
| Jonathan Greenard | DL | Min | 27 | **** | ||
| Akeem Davis-Gaither | LB | Cin | N/A | **** | ||
| Nakobe Dean | LB | Phi | 24 | **** | Questionable | Knee |
| Daiyan Henley | LB | LAC | N/A | **** | Questionable | Shoulder - Labrum |
| Tyrice Knight | LB | Sea | 24 | **** | ||
| Zyon McCollum | CB | TB | N/A | **** | ||
| Brandon Jones | S | Den | 27 | **** |