| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Bo Nix | QB | Den | 25 | **** | ||
| Jayden Daniels | QB | Was | 24 | **** | ||
| Jameis Winston | QB | NYG | 31 | **** | ||
| Bryce Young | QB | Car | 23 | **** | ||
| Jahmyr Gibbs | RB | Det | 23 | **** | ||
| Travis Etienne | RB | Jac | 26 | **** | ||
| Zamir White | RB | LV | 25 | **** | ||
| Jerome Ford | RB | Cle | 25 | **** | Questionable | Ankle |
| David Montgomery | RB | Det | 27 | **** | ||
| Isaac Guerendo | RB | SF | 24 | **** | Questionable | Knee - MCL |
| Jalen McMillan | WR | TB | 23 | **** | ||
| Troy Franklin | WR | Den | 22 | **** | ||
| Malik Washington | WR | Mia | 24 | **** | ||
| Ja'Lynn Polk | WR | NE | 23 | **** | Questionable | Shoulder |
| Roman Wilson | WR | Pit | 23 | **** | ||
| Ladd McConkey | WR | LAC | 23 | **** | ||
| Jerry Jeudy | WR | Cle | 26 | **** | ||
| Brandon Aiyuk | WR | SF | 27 | **** | Questionable | Knee - ACL + MCL |
| Luke McCaffrey | WR | Was | 24 | **** | ||
| Rashid Shaheed | WR | NO | 26 | **** | Questionable | Knee - Meniscus |
| Rashee Rice | WR | KC | 25 | **** | Questionable | Knee |
| Marvin Mims | WR | Den | 23 | **** | ||
| Josh Downs | WR | Ind | 23 | **** | ||
| Michael Wilson | WR | Ari | 25 | **** | Questionable | Hamstring |
| Dontayvion Wicks | WR | GB | 23 | **** | ||
| Jermaine Burton | WR | Cin | 23 | **** | ||
| Pat Freiermuth | TE | Pit | 26 | **** | ||
| Kobie Turner | DL | LAR | N/A | **** | ||
| Leonard Williams | DL | Sea | 30 | **** | ||
| Jared Verse | DL | LAR | 24 | **** | ||
| Eric Kendricks | LB | Dal | 33 | **** | ||
| Bobby Okereke | LB | NYG | 28 | **** | Questionable | Back |
| Kaden Elliss | LB | Atl | 29 | **** |