| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| J.J. McCarthy | QB | Min | 22 | **** | ||
| Deshaun Watson | QB | Cle | 29 | **** | Questionable | Achilles |
| Justin Herbert | QB | LAC | 27 | **** | ||
| Trevor Lawrence | QB | Jac | 25 | **** | Questionable | Shoulder - AC Joint |
| Bryce Young | QB | Car | 23 | **** | ||
| Kyren Williams | RB | LAR | 24 | **** | ||
| David Montgomery | RB | Det | 27 | **** | ||
| D'Andre Swift | RB | Chi | 26 | **** | ||
| Trey Benson | RB | Ari | 22 | **** | Questionable | Ankle |
| Roman Wilson | WR | Pit | 23 | **** | ||
| Ricky Pearsall | WR | SF | 24 | **** | ||
| Adam Thielen | WR | Car | 34 | **** | ||
| Tim Patrick | WR | Det | 31 | **** | ||
| Christian Kirk | WR | Hou | 28 | **** | Questionable | Collarbone |
| Romeo Doubs | WR | GB | 25 | **** | Questionable | Concussion |
| Jaylen Waddle | WR | Mia | 26 | **** | ||
| T.J. Hockenson | TE | Min | 27 | **** | ||
| Cole Kmet | TE | Chi | 26 | **** | ||
| Jake Moody | PK | SF | 25 | **** | ||
| Aidan Hutchinson | DL | Det | 24 | **** | Questionable | Lower leg |
| Josh Hines-Allen | DL | Jac | 27 | **** | ||
| Jared Verse | DL | LAR | 24 | **** | ||
| Bobby Wagner | LB | Was | 34 | **** | ||
| Quay Walker | LB | GB | 24 | **** | ||
| Terrel Bernard | LB | Buf | 25 | **** | ||
| Kaden Elliss | LB | Atl | 29 | **** | ||
| Jack Campbell | LB | Det | 24 | **** | ||
| Riley Moss | CB | Den | N/A | **** | ||
| Jaylon Jones | CB | Ind | N/A | **** | ||
| Nick Cross | S | Ind | N/A | **** | ||
| Tyler Nubin | S | NYG | 23 | **** | Questionable | Ankle |
| Xavier Woods | S | Car | 29 | **** | ||
| Jeremy Chinn | S | Was | 27 | **** |