| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| Derek Carr | QB | NO | 34 | **** | Questionable | Shoulder |
| Trevor Lawrence | QB | Jac | 25 | **** | Questionable | Shoulder - AC Joint |
| Kenneth Gainwell | RB | Pit | 26 | **** | ||
| Kenneth Walker | RB | Sea | 24 | **** | Questionable | Ankle |
| Blake Corum | RB | LAR | 24 | **** | Questionable | Forearm |
| Saquon Barkley | RB | Phi | 28 | **** | ||
| Nick Chubb | RB | Cle | 29 | **** | ||
| Courtland Sutton | WR | Den | 29 | **** | ||
| Demarcus Robinson | WR | SF | 30 | **** | ||
| Mike Williams | WR | LAC | 30 | **** | ||
| Xavier Legette | WR | Car | 24 | **** | Questionable | Foot |
| Amari Cooper | WR | Buf | 30 | **** | ||
| Jamison Crowder | WR | Was | 31 | **** | ||
| Terry McLaurin | WR | Was | 28 | **** | ||
| Puka Nacua | WR | LAR | 23 | **** | ||
| Zach Ertz | TE | Was | 34 | **** | ||
| George Kittle | TE | SF | 31 | **** | ||
| Wil Lutz | PK | Den | 30 | **** | ||
| Tyler Bass | PK | Buf | 28 | **** | ||
| D.J. Wonnum | DL | Car | 27 | **** | ||
| Nik Bonitto | DL | Den | 25 | **** | ||
| Khalil Mack | DL | LAC | 34 | **** | ||
| DeForest Buckner | DL | Ind | 31 | **** | ||
| Danielle Hunter | DL | Hou | 30 | **** | ||
| Roquan Smith | LB | Bal | 28 | **** | ||
| Kyzir White | LB | Ari | 29 | **** | ||
| Azeez Al-Shaair | LB | Hou | 27 | **** | Questionable | Knee |
| T.J. Edwards | LB | Chi | 28 | **** | ||
| Riley Moss | CB | Den | N/A | **** | ||
| Chamarri Conner | CB | KC | N/A | **** | ||
| Kerby Joseph | S | Det | 24 | **** | ||
| Jessie Bates | S | Atl | 28 | **** |