| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Drake Maye | QB | NE | 22 | **** | ||
| Jared Goff | QB | Det | 30 | **** | ||
| Jacoby Brissett | QB | Ari | 32 | **** | ||
| Kareem Hunt | RB | KC | 29 | **** | ||
| Isaac Guerendo | RB | SF | 24 | **** | Questionable | Knee - MCL |
| Antonio Gibson | RB | NE | 26 | **** | ||
| Rachaad White | RB | TB | 26 | **** | ||
| Brian Robinson | RB | Was | 26 | **** | ||
| Zamir White | RB | LV | 25 | **** | ||
| Jahmyr Gibbs | RB | Det | 23 | **** | ||
| Jaleel McLaughlin | RB | Den | 24 | **** | ||
| Marvin Mims | WR | Den | 23 | **** | ||
| Drake London | WR | Atl | 24 | **** | ||
| Khalil Shakir | WR | Buf | 25 | **** | ||
| Xavier Worthy | WR | KC | 22 | **** | ||
| Tyreek Hill | WR | Mia | 31 | **** | Questionable | Wrist |
| Allen Lazard | WR | NYJ | 29 | **** | ||
| Brandon Aiyuk | WR | SF | 27 | **** | Questionable | Knee - ACL + MCL |
| Brock Bowers | TE | LV | 22 | **** | ||
| Jake Ferguson | TE | Dal | 26 | **** | ||
| Harrison Butker | PK | KC | 29 | **** | ||
| Rashan Gary | DL | GB | 27 | **** | ||
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| Trey Hendrickson | DL | Cin | 30 | **** | ||
| Odafe Oweh | DL | Bal | 26 | **** | ||
| Ernest Jones | LB | Sea | 25 | **** | Questionable | Knee |
| Alex Singleton | LB | Den | 31 | **** | Questionable | Knee - ACL |
| Blake Cashman | LB | Min | 28 | **** | ||
| Fred Warner | LB | SF | 28 | **** | ||
| Patrick Queen | LB | Pit | 25 | **** | ||
| Nate Hobbs | CB | LV | 25 | **** | ||
| Christian Izien | S | TB | N/A | **** | Questionable | Pectoral |
| Antoine Winfield | S | TB | 26 | **** |