| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Sam Darnold | QB | Sea | 27 | **** | ||
| Trevor Lawrence | QB | Jac | 25 | **** | Questionable | Shoulder - AC Joint |
| Brock Purdy | QB | SF | 25 | **** | ||
| Jaylen Warren | RB | Pit | 26 | **** | ||
| Javonte Williams | RB | Dal | 25 | **** | ||
| Michael Carter | RB | Ari | 25 | **** | ||
| James Cook | RB | Buf | 25 | **** | ||
| Saquon Barkley | RB | Phi | 28 | **** | ||
| Rico Dowdle | RB | Car | 26 | **** | ||
| Craig Reynolds | RB | Det | 28 | **** | ||
| CeeDee Lamb | WR | Dal | 26 | **** | ||
| Keon Coleman | WR | Buf | 21 | **** | ||
| Malik Nabers | WR | NYG | 21 | **** | ||
| Ricky Pearsall | WR | SF | 24 | **** | ||
| Jalen Tolbert | WR | Dal | 26 | **** | ||
| Alec Pierce | WR | Ind | 25 | **** | ||
| Isaiah Likely | TE | Bal | 25 | **** | ||
| Sam LaPorta | TE | Det | 24 | **** | ||
| Dalton Schultz | TE | Hou | 28 | **** | ||
| Kyle Pitts | TE | Atl | 24 | **** | ||
| Ka'imi Fairbairn | PK | Hou | 31 | **** | ||
| Josh Sweat | DL | Ari | 28 | **** | ||
| Chop Robinson | DL | Mia | 22 | **** | ||
| Greg Rousseau | DL | Buf | 25 | **** | ||
| Kayvon Thibodeaux | DL | NYG | 24 | **** | ||
| Devin Lloyd | LB | Jac | 26 | **** | ||
| Terrel Bernard | LB | Buf | 25 | **** | ||
| Daiyan Henley | LB | LAC | N/A | **** | Questionable | Shoulder - Labrum |
| Dre Greenlaw | LB | Den | 27 | **** | Questionable | Quadriceps |
| Lavonte David | LB | TB | 35 | **** | ||
| Matt Milano | LB | Buf | 30 | **** | ||
| Devon Witherspoon | CB | Sea | 24 | **** | ||
| Brandon Jones | S | Den | 27 | **** |