| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Kyler Murray | QB | Ari | 27 | **** | ||
| Trevor Lawrence | QB | Jac | 25 | **** | Questionable | Shoulder - AC Joint |
| Mac Jones | QB | Jac | 26 | **** | ||
| Trey Sermon | RB | Ind | 26 | **** | ||
| Kene Nwangwu | RB | NYJ | 27 | **** | ||
| Breece Hall | RB | NYJ | 23 | **** | ||
| Kenneth Walker | RB | Sea | 24 | **** | Questionable | Ankle |
| Rachaad White | RB | TB | 26 | **** | ||
| Antonio Gibson | RB | NE | 26 | **** | ||
| Ezekiel Elliott | RB | Dal | 29 | **** | ||
| Ricky Pearsall | WR | SF | 24 | **** | ||
| Demario Douglas | WR | NE | 24 | **** | ||
| Garrett Wilson | WR | NYJ | 24 | **** | ||
| Christian Watson | WR | GB | 25 | **** | Questionable | Knee - ACL |
| Amon-Ra St. Brown | WR | Det | 25 | **** | ||
| Ray-Ray McCloud | WR | Atl | 28 | **** | ||
| Gabriel Davis | WR | Jac | 26 | **** | Questionable | Knee - Meniscus |
| Brock Bowers | TE | LV | 22 | **** | ||
| Mark Andrews | TE | Bal | 28 | **** | ||
| Ka'imi Fairbairn | PK | Hou | 31 | **** | ||
| Younghoe Koo | PK | Atl | 30 | **** | Questionable | Hip |
| Harold Landry | DL | Ten | 28 | **** | ||
| Chris Jones | DL | KC | 30 | **** | ||
| Brian Burns | DL | NYG | 27 | **** | ||
| Maxx Crosby | DL | LV | 27 | **** | Questionable | Ankle |
| Lavonte David | LB | TB | 35 | **** | ||
| Nick Bolton | LB | KC | 25 | **** | ||
| Dorian Williams | LB | Buf | 23 | **** | ||
| Henry To'oTo'o | LB | Hou | N/A | **** | ||
| Cam Taylor-Britt | CB | Cin | 25 | **** | ||
| Carlton Davis | CB | Det | 28 | **** | ||
| Xavier McKinney | S | GB | 36 | **** | ||
| Brandon Jones | S | Den | 27 | **** |