| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Bo Nix | QB | Den | 25 | **** | ||
| Patrick Mahomes | QB | KC | 29 | **** | ||
| Christian McCaffrey | RB | SF | 28 | **** | ||
| Isaac Guerendo | RB | SF | 24 | **** | Questionable | Knee - MCL |
| Bucky Irving | RB | TB | 22 | **** | ||
| Patrick Taylor | RB | SF | 27 | **** | ||
| Travis Etienne | RB | Jac | 26 | **** | ||
| Isiah Pacheco | RB | KC | 26 | **** | ||
| Jordan Mason | RB | Min | 25 | **** | Questionable | Ankle |
| Emari Demercado | RB | Ari | 26 | **** | Questionable | Back |
| Sean Tucker | RB | TB | N/A | **** | ||
| Calvin Austin | WR | Pit | 26 | **** | ||
| Zay Flowers | WR | Bal | 24 | **** | Questionable | Knee |
| Cedric Tillman | WR | Cle | 25 | **** | Questionable | Concussion |
| Dontayvion Wicks | WR | GB | 23 | **** | ||
| Parker Washington | WR | Jac | 23 | **** | ||
| Andrei Iosivas | WR | Cin | 25 | **** | ||
| Jameson Williams | WR | Det | 24 | **** | ||
| Courtland Sutton | WR | Den | 29 | **** | ||
| Devaughn Vele | WR | Den | 27 | **** | ||
| Mike Williams | WR | LAC | 30 | **** | ||
| Chris Godwin | WR | TB | 29 | **** | Questionable | Ankle |
| Jonnu Smith | TE | Mia | 29 | **** | ||
| T.J. Hockenson | TE | Min | 27 | **** | ||
| Cade Otton | TE | TB | 26 | **** | ||
| Justin Tucker | PK | Bal | 35 | **** | ||
| Andrew Van Ginkel | DL | Min | 29 | **** | ||
| Jonathon Cooper | DL | Den | 27 | **** | ||
| Aidan Hutchinson | DL | Det | 24 | **** | Questionable | Lower leg |
| Zaven Collins | DL | Ari | 25 | **** | ||
| Derick Hall | DL | Sea | 24 | **** | ||
| Troy Andersen | LB | Atl | 26 | **** | Questionable | Knee |
| Christian Rozeboom | LB | LAR | N/A | **** |