| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| Justin Fields | QB | NYJ | 26 | **** | ||
| Bryce Young | QB | Car | 23 | **** | ||
| Matthew Stafford | QB | LAR | 37 | **** | ||
| Jaleel McLaughlin | RB | Den | 24 | **** | ||
| Tyler Allgeier | RB | Atl | 25 | **** | ||
| Kendre Miller | RB | NO | 22 | **** | Questionable | Concussion |
| Tyjae Spears | RB | Ten | 23 | **** | Questionable | Concussion |
| De'Von Achane | RB | Mia | 23 | **** | ||
| Tony Pollard | RB | Ten | 28 | **** | ||
| Josh Jacobs | RB | GB | 27 | **** | ||
| Jalen McMillan | WR | TB | 23 | **** | ||
| Adam Thielen | WR | Car | 34 | **** | ||
| Tyler Lockett | WR | Sea | 32 | **** | ||
| CeeDee Lamb | WR | Dal | 26 | **** | ||
| Tee Higgins | WR | Cin | 26 | **** | ||
| Nico Collins | WR | Hou | 26 | **** | ||
| George Kittle | TE | SF | 31 | **** | ||
| Chig Okonkwo | TE | Ten | 26 | **** | ||
| Brandon McManus | PK | GB | 33 | **** | ||
| Jake Moody | PK | SF | 25 | **** | ||
| Alex Highsmith | DL | Pit | 27 | **** | ||
| Will Anderson | DL | Hou | 23 | **** | ||
| Nick Bosa | DL | SF | 27 | **** | ||
| A'Shawn Robinson | DL | Car | 30 | **** | Questionable | Calf |
| Ernest Jones | LB | Sea | 25 | **** | Questionable | Knee |
| Christian Harris | LB | Hou | N/A | **** | ||
| Terrel Bernard | LB | Buf | 25 | **** | ||
| Zack Baun | LB | Phi | 28 | **** | ||
| Mike Sainristil | CB | Was | 24 | **** | ||
| Tyrique Stevenson | CB | Chi | 24 | **** | ||
| Taylor Rapp | S | Buf | 27 | **** | ||
| Julian Love | S | Sea | 27 | **** |