| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jared Goff | QB | Det | 30 | **** | ||
| Daniel Jones | QB | Ind | 27 | **** | ||
| J.K. Dobbins | RB | LAC | 26 | **** | ||
| James Conner | RB | Ari | 29 | **** | Questionable | Knee |
| Austin Ekeler | RB | Was | 29 | **** | ||
| MarShawn Lloyd | RB | GB | 24 | **** | Questionable | Hamstring |
| Blake Corum | RB | LAR | 24 | **** | Questionable | Forearm |
| Roschon Johnson | RB | Chi | 24 | **** | ||
| Chase Brown | RB | Cin | 25 | **** | Questionable | Ankle |
| Rashod Bateman | WR | Bal | 25 | **** | ||
| Jameson Williams | WR | Det | 24 | **** | ||
| George Pickens | WR | Pit | 23 | **** | ||
| Mike Evans | WR | TB | 31 | **** | ||
| Xavier Worthy | WR | KC | 22 | **** | ||
| Jake Ferguson | TE | Dal | 26 | **** | ||
| Noah Gray | TE | KC | N/A | **** | ||
| Jason Myers | PK | Sea | 33 | **** | ||
| Ka'imi Fairbairn | PK | Hou | 31 | **** | ||
| Leonard Floyd | DL | Atl | 32 | **** | ||
| Jared Verse | DL | LAR | 24 | **** | ||
| Sam Hubbard | DL | Cin | 28 | **** | personal | |
| Zach Sieler | DL | Mia | 29 | **** | ||
| Aidan Hutchinson | DL | Det | 24 | **** | Questionable | Lower leg |
| Alex Highsmith | DL | Pit | 27 | **** | ||
| Christian Rozeboom | LB | LAR | N/A | **** | ||
| Henry To'oTo'o | LB | Hou | N/A | **** | ||
| Mack Wilson | LB | Ari | 27 | **** | ||
| Patrick Queen | LB | Pit | 25 | **** | ||
| Marlon Humphrey | CB | Bal | 28 | **** | ||
| Zyon McCollum | CB | TB | N/A | **** | ||
| Julian Blackmon | S | Ind | 26 | **** | ||
| Derwin James | S | LAC | 28 | **** |