| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Drake Maye | QB | NE | 22 | **** | ||
| Carson Wentz | QB | KC | 32 | **** | ||
| Patrick Mahomes | QB | KC | 29 | **** | ||
| Joe Mixon | RB | Hou | 28 | **** | ||
| Alvin Kamara | RB | NO | 29 | **** | Questionable | Groin |
| Kareem Hunt | RB | KC | 29 | **** | ||
| Jamaal Williams | RB | NO | 30 | **** | ||
| Antonio Gibson | RB | NE | 26 | **** | ||
| Dameon Pierce | RB | Hou | 25 | **** | ||
| Isiah Pacheco | RB | KC | 26 | **** | ||
| Kendre Miller | RB | NO | 22 | **** | Questionable | Concussion |
| Roschon Johnson | RB | Chi | 24 | **** | ||
| Dontayvion Wicks | WR | GB | 23 | **** | ||
| Rashee Rice | WR | KC | 25 | **** | Questionable | Knee |
| CeeDee Lamb | WR | Dal | 26 | **** | ||
| Tyreek Hill | WR | Mia | 31 | **** | Questionable | Wrist |
| DeAndre Hopkins | WR | Bal | 32 | **** | ||
| Adam Thielen | WR | Car | 34 | **** | ||
| Tyler Lockett | WR | Sea | 32 | **** | ||
| David Njoku | TE | Cle | 28 | **** | Questionable | Knee |
| Chig Okonkwo | TE | Ten | 26 | **** | ||
| Brandon McManus | PK | GB | 33 | **** | ||
| Za'Darius Smith | DL | Det | 32 | **** | ||
| DeForest Buckner | DL | Ind | 31 | **** | ||
| Zach Allen | DL | Den | 27 | **** | ||
| Carl Granderson | DL | NO | 28 | **** | ||
| Christian Rozeboom | LB | LAR | N/A | **** | ||
| Micah McFadden | LB | NYG | 25 | **** | Questionable | Neck |
| Ernest Jones | LB | Sea | 25 | **** | Questionable | Knee |
| Patrick Queen | LB | Pit | 25 | **** | ||
| Zyon McCollum | CB | TB | N/A | **** | ||
| Jaycee Horn | CB | Car | 25 | **** | ||
| Trevon Moehrig | S | LV | 25 | **** |