| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| Cooper Rush | QB | Dal | N/A | **** | ||
| Anthony Richardson | QB | Ind | 22 | **** | Questionable | Back |
| Najee Harris | RB | LAC | 27 | **** | ||
| Travis Etienne | RB | Jac | 26 | **** | ||
| Tyler Goodson | RB | Ind | N/A | **** | ||
| Dare Ogunbowale | RB | Hou | 30 | **** | ||
| Jamaal Williams | RB | NO | 30 | **** | ||
| Alexander Mattison | RB | Mia | 26 | **** | ||
| Keon Coleman | WR | Buf | 21 | **** | ||
| Brandin Cooks | WR | NO | 31 | **** | ||
| Tyreek Hill | WR | Mia | 31 | **** | Questionable | Wrist |
| Alec Pierce | WR | Ind | 25 | **** | ||
| Romeo Doubs | WR | GB | 25 | **** | Questionable | Concussion |
| Calvin Austin | WR | Pit | 26 | **** | ||
| Khalil Shakir | WR | Buf | 25 | **** | ||
| Cedric Tillman | WR | Cle | 25 | **** | Questionable | Concussion |
| Tre Tucker | WR | LV | N/A | **** | ||
| David Njoku | TE | Cle | 28 | **** | Questionable | Knee |
| Jonnu Smith | TE | Mia | 29 | **** | ||
| Harrison Butker | PK | KC | 29 | **** | ||
| Matt Gay | PK | Ind | 31 | **** | ||
| Tyler Bass | PK | Buf | 28 | **** | ||
| Carl Granderson | DL | NO | 28 | **** | ||
| A.J. Epenesa | DL | Buf | 26 | **** | ||
| Jonathan Greenard | DL | Min | 27 | **** | ||
| Quincy Williams | LB | NYJ | 28 | **** | ||
| Zaire Franklin | LB | Ind | 28 | **** | ||
| Quay Walker | LB | GB | 24 | **** | ||
| Dorian Williams | LB | Buf | 23 | **** | ||
| Charvarius Ward | CB | SF | 28 | **** | ||
| Jessie Bates | S | Atl | 28 | **** | ||
| Kevin Byard | S | Chi | 31 | **** |