| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Patrick Mahomes | QB | KC | 29 | **** | ||
| Tom Brady | QB | F/A | 47 | **** | ||
| Kendre Miller | RB | NO | 22 | **** | Questionable | Concussion |
| Elijah Mitchell | RB | KC | 27 | **** | ||
| Khalil Herbert | RB | Ind | 27 | **** | ||
| Dameon Pierce | RB | Hou | 25 | **** | ||
| Ty Chandler | RB | Min | 26 | **** | ||
| Joe Mixon | RB | Hou | 28 | **** | ||
| Kareem Hunt | RB | KC | 29 | **** | ||
| Ray Davis | RB | Buf | 25 | **** | ||
| Ameer Abdullah | RB | LV | 31 | **** | ||
| Cam Akers | RB | Min | 25 | **** | ||
| Patrick Taylor | RB | SF | 27 | **** | ||
| Michael Carter | RB | Ari | 25 | **** | ||
| Amari Cooper | WR | Buf | 30 | **** | ||
| Ja'Marr Chase | WR | Cin | 25 | **** | ||
| Elijah Moore | WR | Cle | 25 | **** | ||
| Tyreek Hill | WR | Mia | 31 | **** | Questionable | Wrist |
| D.J. Moore | WR | Chi | 28 | **** | ||
| KaVontae Turpin | WR | Dal | N/A | **** | ||
| Tre Tucker | WR | LV | N/A | **** | ||
| Cade Otton | TE | TB | 26 | **** | ||
| Sam LaPorta | TE | Det | 24 | **** | ||
| T.J. Hockenson | TE | Min | 27 | **** | ||
| Noah Gray | TE | KC | N/A | **** | ||
| Cameron Dicker | PK | LAC | 24 | **** | ||
| Nik Bonitto | DL | Den | 25 | **** | ||
| Alex Highsmith | DL | Pit | 27 | **** | ||
| Chop Robinson | DL | Mia | 22 | **** | ||
| Jamien Sherwood | LB | NYJ | 25 | **** | ||
| Jack Campbell | LB | Det | 24 | **** | ||
| Ivan Pace | LB | Min | 24 | **** | ||
| Daiyan Henley | LB | LAC | N/A | **** | Questionable | Shoulder - Labrum |