| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jared Goff | QB |
|
31 | No More Bye | ||
| Nick Chubb | RB |
|
29 | No More Bye | Questionable | Ribs |
| James Conner | RB |
|
30 | No More Bye | NFI | Foot |
| Emari Demercado | RB |
|
26 | No More Bye | Questionable | Ankle |
| Jerome Ford | RB |
|
26 | No More Bye | NFI | Shoulder |
| TreVeyon Henderson | RB |
|
23 | No More Bye | ||
| Josh Jacobs | RB |
|
27 | No More Bye | Questionable | Knee |
| Zonovan Knight | RB |
|
24 | No More Bye | ||
| Dylan Sampson | RB |
|
21 | No More Bye | Out | Calf |
| Isaiah Bond | WR |
|
21 | No More Bye | ||
| A.J. Brown | WR |
|
28 | No More Bye | ||
| Jalen Coker | WR |
|
24 | No More Bye | ||
| Chris Godwin | WR |
|
29 | No More Bye | ||
| Tyreek Hill | WR |
|
31 | No More Bye | NFI | Knee - ACL |
| Quentin Johnston | WR |
|
24 | No More Bye | ||
| Christian Kirk | WR |
|
29 | No More Bye | ||
| Jakobi Meyers | WR |
|
29 | No More Bye | ||
| Wan'Dale Robinson | WR |
|
24 | No More Bye | ||
| Amon-Ra St. Brown | WR |
|
26 | No More Bye | ||
| Tyquan Thornton | WR |
|
25 | No More Bye | ||
| Jaylen Waddle | WR |
|
27 | No More Bye | ||
| Hunter Henry | TE |
|
31 | No More Bye | ||
| Jake Moody | PK |
|
26 | No More Bye | ||
| Javon Hargrave | DL |
|
32 | No More Bye | ||
| Derrick Harmon | DL |
|
22 | No More Bye | Questionable | Knee |
| Aidan Hutchinson | DL |
|
25 | No More Bye | ||
| Kwity Paye | DL |
|
27 | No More Bye | ||
| Teddye Buchanan | LB |
|
23 | No More Bye | ||
| Shemar James | LB |
|
21 | No More Bye | ||
| Nate Landman | LB |
|
27 | No More Bye | ||
| Pete Werner | LB |
|
26 | No More Bye | ||
| Roger McCreary | CB |
|
25 | No More Bye | NFI | Hip |
| Kevin Byard | S |
|
32 | No More Bye |