| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jayden Daniels | QB | Was | 24 | **** | ||
| Brock Purdy | QB | SF | 25 | **** | ||
| Bryce Young | QB | Car | 23 | **** | ||
| Kenneth Walker | RB | Sea | 24 | **** | Questionable | Ankle |
| Jerome Ford | RB | Cle | 25 | **** | Questionable | Ankle |
| Roschon Johnson | RB | Chi | 24 | **** | ||
| Isaiah Davis | RB | NYJ | 23 | **** | ||
| Isaac Guerendo | RB | SF | 24 | **** | Questionable | Knee - MCL |
| Ameer Abdullah | RB | LV | 31 | **** | ||
| Kareem Hunt | RB | KC | 29 | **** | ||
| Jeremy McNichols | RB | Was | 29 | **** | ||
| Josh Jacobs | RB | GB | 27 | **** | ||
| D.K. Metcalf | WR | Pit | 27 | **** | ||
| Luke McCaffrey | WR | Was | 24 | **** | ||
| George Pickens | WR | Pit | 23 | **** | ||
| Marvin Mims | WR | Den | 23 | **** | ||
| Josh Downs | WR | Ind | 23 | **** | ||
| Jordan Addison | WR | Min | 23 | **** | ||
| Nico Collins | WR | Hou | 26 | **** | ||
| Amon-Ra St. Brown | WR | Det | 25 | **** | ||
| Sam LaPorta | TE | Det | 24 | **** | ||
| Brenton Strange | TE | Jac | N/A | **** | ||
| Mark Andrews | TE | Bal | 28 | **** | ||
| Jake Moody | PK | SF | 25 | **** | ||
| Micah Parsons | DL | Dal | 26 | **** | ||
| Jared Verse | DL | LAR | 24 | **** | ||
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| Carl Granderson | DL | NO | 28 | **** | ||
| Kaden Elliss | LB | Atl | 29 | **** | ||
| Josey Jewell | LB | Car | 30 | **** | Questionable | Concussion |
| T.J. Edwards | LB | Chi | 28 | **** | ||
| Keisean Nixon | CB | GB | N/A | **** | ||
| Brandon Jones | S | Den | 27 | **** |