| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Michael Penix Jr. | QB | Atl | 24 | **** | ||
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| Baker Mayfield | QB | TB | 30 | **** | ||
| Kyler Murray | QB | Ari | 27 | **** | ||
| Gus Edwards | RB | LAC | 30 | **** | ||
| Dalvin Cook | RB | Dal | 29 | **** | ||
| Najee Harris | RB | LAC | 27 | **** | ||
| Javonte Williams | RB | Dal | 25 | **** | ||
| Tyjae Spears | RB | Ten | 23 | **** | Questionable | Concussion |
| Roschon Johnson | RB | Chi | 24 | **** | ||
| Wan'Dale Robinson | WR | NYG | 24 | **** | ||
| Josh Palmer | WR | Buf | 25 | **** | ||
| Gabriel Davis | WR | Jac | 26 | **** | Questionable | Knee - Meniscus |
| Davante Adams | WR | LAR | 32 | **** | ||
| Marvin Harrison Jr. | WR | Ari | 22 | **** | ||
| Diontae Johnson | WR | Hou | 28 | **** | ||
| Darius Slayton | WR | NYG | 28 | **** | ||
| Foster Moreau | TE | NO | 27 | **** | Questionable | Knee |
| Kyle Pitts | TE | Atl | 24 | **** | ||
| Trey McBride | TE | Ari | 25 | **** | ||
| Jake Elliott | PK | Phi | 30 | **** | ||
| Daniel Carlson | PK | LV | 30 | **** | ||
| Evan Anderson | DL | SF | 23 | **** | ||
| A.J. Epenesa | DL | Buf | 26 | **** | ||
| Kwity Paye | DL | Ind | 26 | **** | ||
| Devonte Wyatt | DL | GB | N/A | **** | ||
| Quay Walker | LB | GB | 24 | **** | ||
| Jordyn Brooks | LB | Mia | 27 | **** | Questionable | Wrist |
| Patrick Queen | LB | Pit | 25 | **** | ||
| Frankie Luvu | LB | Was | 28 | **** | ||
| Tyrique Stevenson | CB | Chi | 24 | **** | ||
| Reed Blankenship | S | Phi | 26 | **** | ||
| Julian Blackmon | S | Ind | 26 | **** |