| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Drake Maye | QB | NE | 22 | **** | ||
| Jared Goff | QB | Det | 30 | **** | ||
| Josh Jacobs | RB | GB | 27 | **** | ||
| Ameer Abdullah | RB | LV | 31 | **** | ||
| Tyrone Tracy Jr. | RB | NYG | 25 | **** | ||
| Isaiah Davis | RB | NYJ | 23 | **** | ||
| Trey Benson | RB | Ari | 22 | **** | Questionable | Ankle |
| Sean Tucker | RB | TB | N/A | **** | ||
| Tank Dell | WR | Hou | 25 | **** | Questionable | Knee - ACL + MCL |
| Zay Flowers | WR | Bal | 24 | **** | Questionable | Knee |
| Ladd McConkey | WR | LAC | 23 | **** | ||
| Adam Thielen | WR | Car | 34 | **** | ||
| Tyler Lockett | WR | Sea | 32 | **** | ||
| Michael Pittman | WR | Ind | 27 | **** | ||
| Amon-Ra St. Brown | WR | Det | 25 | **** | ||
| Brock Bowers | TE | LV | 22 | **** | ||
| Tucker Kraft | TE | GB | N/A | **** | ||
| Jake Moody | PK | SF | 25 | **** | ||
| K'Lavon Chaisson | DL | LV | 25 | **** | ||
| Keion White | DL | NE | N/A | **** | ||
| Will McDonald | DL | NYJ | N/A | **** | ||
| Calijah Kancey | DL | TB | N/A | **** | ||
| Leonard Williams | DL | Sea | 30 | **** | ||
| Eric Kendricks | LB | Dal | 33 | **** | ||
| Marist Liufau | LB | Dal | 24 | **** | ||
| Darius Muasau | LB | NYG | 24 | **** | ||
| Bobby Okereke | LB | NYG | 28 | **** | Questionable | Back |
| Alontae Taylor | CB | NO | N/A | **** | ||
| Dane Belton | S | NYG | N/A | **** | ||
| Jeremy Chinn | S | Was | 27 | **** | ||
| Brandon Jones | S | Den | 27 | **** |