| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Justin Herbert | QB |
|
27 | No More Bye | ||
| Shedeur Sanders | QB |
|
23 | No More Bye | ||
| Tyler Shough | QB |
|
26 | No More Bye | ||
| DJ Giddens | RB |
|
22 | No More Bye | ||
| RJ Harvey | RB |
|
24 | No More Bye | ||
| Alvin Kamara | RB |
|
30 | No More Bye | Out | Knee - MCL |
| MarShawn Lloyd | RB |
|
24 | No More Bye | NFI | Calf |
| Devin Neal | RB |
|
22 | No More Bye | ||
| Zamir White | RB |
|
26 | No More Bye | ||
| Jaylen Wright | RB |
|
22 | No More Bye | ||
| Josh Downs | WR |
|
24 | No More Bye | ||
| Emeka Egbuka | WR |
|
23 | No More Bye | ||
| Matthew Golden | WR |
|
22 | No More Bye | ||
| Xavier Hutchinson | WR |
|
N/A | No More Bye | ||
| Tez Johnson | WR |
|
23 | No More Bye | ||
| Quentin Johnston | WR |
|
24 | No More Bye | Questionable | Groin |
| Alec Pierce | WR |
|
25 | No More Bye | ||
| Xavier Worthy | WR |
|
22 | No More Bye | ||
| Dalton Kincaid | TE |
|
27 | No More Bye | ||
| Mason Taylor | TE |
|
21 | No More Bye | Out | Neck |
| Charlie Smyth | PK |
|
24 | No More Bye | ||
| Joey Bosa | DL |
|
30 | No More Bye | ||
| Cameron Jordan | DL |
|
36 | No More Bye | ||
| Byron Murphy II | DL |
|
23 | No More Bye | ||
| Jalon Walker | DL |
|
21 | No More Bye | ||
| Jack Campbell | LB |
|
25 | No More Bye | ||
| Jihaad Campbell | LB |
|
21 | No More Bye | ||
| Akeem Davis-Gaither | LB |
|
N/A | No More Bye | ||
| Carson Schwesinger | LB |
|
22 | No More Bye | ||
| Justin Strnad | LB |
|
N/A | No More Bye | ||
| Tyrique Stevenson | CB |
|
25 | No More Bye | ||
| Talanoa Hufanga | S |
|
26 | No More Bye | ||
| Quentin Lake | S |
|
N/A | No More Bye | NFI | Elbow |