| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jalen Hurts | QB | Phi | 26 | **** | ||
| Matthew Stafford | QB | LAR | 37 | **** | ||
| Jaylen Warren | RB | Pit | 26 | **** | ||
| Rachaad White | RB | TB | 26 | **** | ||
| Brian Robinson | RB | Was | 26 | **** | ||
| Kyren Williams | RB | LAR | 24 | **** | ||
| J.K. Dobbins | RB | LAC | 26 | **** | ||
| Alexander Mattison | RB | Mia | 26 | **** | ||
| Brandon Aiyuk | WR | SF | 27 | **** | Questionable | Knee - ACL + MCL |
| Michael Pittman | WR | Ind | 27 | **** | ||
| Deebo Samuel | WR | SF | 29 | **** | ||
| Terry McLaurin | WR | Was | 28 | **** | ||
| Calvin Austin | WR | Pit | 26 | **** | ||
| Jaylen Waddle | WR | Mia | 26 | **** | ||
| Wan'Dale Robinson | WR | NYG | 24 | **** | ||
| Jayden Reed | WR | GB | 25 | **** | Questionable | Shoulder |
| Michael Wilson | WR | Ari | 25 | **** | Questionable | Hamstring |
| Noah Gray | TE | KC | N/A | **** | ||
| George Kittle | TE | SF | 31 | **** | ||
| Cameron Dicker | PK | LAC | 24 | **** | ||
| Patrick Jones II | DL | Min | 26 | **** | ||
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| A.J. Epenesa | DL | Buf | 26 | **** | ||
| Zack Baun | LB | Phi | 28 | **** | ||
| E.J. Speed | LB | Ind | 29 | **** | ||
| Tremaine Edmunds | LB | Chi | 27 | **** | ||
| Fred Warner | LB | SF | 28 | **** | ||
| Demario Davis | LB | NO | 36 | **** | ||
| Nate Landman | LB | Atl | 26 | **** | ||
| Chamarri Conner | CB | KC | N/A | **** | ||
| Christian Benford | CB | Buf | N/A | **** | ||
| Rasul Douglas | CB | Buf | 29 | **** | ||
| Harrison Smith | S | Min | 36 | **** | ||
| Julian Blackmon | S | Ind | 26 | **** |