| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Patrick Mahomes | QB | KC | 29 | **** | ||
| Sam Darnold | QB | Sea | 27 | **** | ||
| Brock Purdy | QB | SF | 25 | **** | ||
| Trey Sermon | RB | Ind | 26 | **** | ||
| Tyjae Spears | RB | Ten | 23 | **** | Questionable | Concussion |
| Nick Chubb | RB | Cle | 29 | **** | ||
| Kimani Vidal | RB | LAC | 23 | **** | ||
| Gus Edwards | RB | LAC | 30 | **** | ||
| J.K. Dobbins | RB | LAC | 26 | **** | ||
| Zack Moss | RB | Cin | 27 | **** | Questionable | Neck |
| Patrick Taylor | RB | SF | 27 | **** | ||
| Nick Westbrook-Ikhine | WR | Mia | 28 | **** | ||
| DeVonta Smith | WR | Phi | 26 | **** | ||
| Josh Palmer | WR | Buf | 25 | **** | ||
| Brian Thomas Jr. | WR | Jac | 22 | **** | ||
| Rashid Shaheed | WR | NO | 26 | **** | Questionable | Knee - Meniscus |
| Puka Nacua | WR | LAR | 23 | **** | ||
| Deebo Samuel | WR | SF | 29 | **** | ||
| Zach Ertz | TE | Was | 34 | **** | ||
| Mike Gesicki | TE | Cin | 29 | **** | ||
| George Kittle | TE | SF | 31 | **** | ||
| Cameron Dicker | PK | LAC | 24 | **** | ||
| Calijah Kancey | DL | TB | N/A | **** | ||
| Derick Hall | DL | Sea | 24 | **** | ||
| Khalil Mack | DL | LAC | 34 | **** | ||
| Frankie Luvu | LB | Was | 28 | **** | ||
| Robert Spillane | LB | LV | 29 | **** | ||
| Quay Walker | LB | GB | 24 | **** | ||
| Kenneth Murray | LB | Ten | 26 | **** | ||
| Chamarri Conner | CB | KC | N/A | **** | ||
| Byron Murphy | CB | Min | 27 | **** | ||
| Camryn Bynum | S | Min | 26 | **** | ||
| Nick Cross | S | Ind | N/A | **** |