| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jordan Love | QB |
|
27 | No More Bye | ||
| Brock Purdy | QB |
|
25 | No More Bye | ||
| Trey Benson | RB |
|
23 | No More Bye | NFI | Knee - Meniscus |
| Chase Brown | RB |
|
25 | No More Bye | ||
| James Cook | RB |
|
26 | No More Bye | ||
| Jacory Croskey-Merritt | RB |
|
24 | No More Bye | ||
| Jordan Mason | RB |
|
26 | No More Bye | ||
| Jaleel McLaughlin | RB |
|
25 | No More Bye | ||
| Kendre Miller | RB |
|
23 | No More Bye | NFI | Knee - ACL |
| Brashard Smith | RB |
|
22 | No More Bye | ||
| Jaylen Wright | RB |
|
22 | No More Bye | ||
| A.J. Brown | WR |
|
28 | No More Bye | ||
| Pat Bryant | WR |
|
23 | No More Bye | Out | Hamstring |
| Zay Flowers | WR |
|
25 | No More Bye | ||
| Matthew Golden | WR |
|
22 | No More Bye | ||
| Tyreek Hill | WR |
|
31 | No More Bye | NFI | Knee - ACL |
| Adonai Mitchell | WR |
|
23 | No More Bye | ||
| Rome Odunze | WR |
|
23 | No More Bye | Questionable | Foot |
| Michael Wilson | WR |
|
25 | No More Bye | ||
| Harold Fannin Jr. | TE |
|
21 | No More Bye | ||
| Oronde Gadsden | TE |
|
22 | No More Bye | ||
| Trey McBride | TE |
|
26 | No More Bye | ||
| Brenton Strange | TE |
|
N/A | No More Bye | ||
| Andy Borregales | PK |
|
23 | No More Bye | ||
| Nik Bonitto | DL |
|
26 | No More Bye | ||
| Jonathon Cooper | DL |
|
27 | No More Bye | ||
| Jack Campbell | LB |
|
25 | No More Bye | ||
| Barrett Carter | LB |
|
23 | No More Bye | ||
| Blake Cashman | LB |
|
29 | No More Bye | ||
| Daiyan Henley | LB |
|
N/A | No More Bye | ||
| Demetrius Knight Jr. | LB |
|
25 | No More Bye | ||
| Jamien Sherwood | LB |
|
25 | No More Bye | ||
| Chamarri Conner | CB |
|
N/A | No More Bye |