| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Baker Mayfield | QB | TB | 30 | **** | ||
| Trevor Lawrence | QB | Jac | 25 | **** | Questionable | Shoulder - AC Joint |
| Aidan O'Connell | QB | LV | N/A | **** | ||
| Justice Hill | RB | Bal | 27 | **** | ||
| Brian Robinson | RB | Was | 26 | **** | ||
| Sincere McCormick | RB | LV | N/A | **** | ||
| Joe Mixon | RB | Hou | 28 | **** | ||
| Ray Davis | RB | Buf | 25 | **** | ||
| Rome Odunze | WR | Chi | 22 | **** | ||
| Malik Nabers | WR | NYG | 21 | **** | ||
| Ladd McConkey | WR | LAC | 23 | **** | ||
| Adam Thielen | WR | Car | 34 | **** | ||
| Tyler Lockett | WR | Sea | 32 | **** | ||
| Deebo Samuel | WR | SF | 29 | **** | ||
| Jordan Addison | WR | Min | 23 | **** | ||
| Jalen Tolbert | WR | Dal | 26 | **** | ||
| Dalton Kincaid | TE | Buf | 26 | **** | ||
| Cade Otton | TE | TB | 26 | **** | ||
| Cameron Dicker | PK | LAC | 24 | **** | ||
| Chris Boswell | PK | Pit | 34 | **** | ||
| Demarcus Lawrence | DL | Dal | 33 | **** | ||
| Harold Landry | DL | Ten | 28 | **** | ||
| Maxx Crosby | DL | LV | 27 | **** | Questionable | Ankle |
| Zaven Collins | DL | Ari | 25 | **** | ||
| Aidan Hutchinson | DL | Det | 24 | **** | Questionable | Lower leg |
| Henry To'oTo'o | LB | Hou | N/A | **** | ||
| Germaine Pratt | LB | Cin | 28 | **** | ||
| Eric Kendricks | LB | Dal | 33 | **** | ||
| Bobby Wagner | LB | Was | 34 | **** | ||
| Tyrique Stevenson | CB | Chi | 24 | **** | ||
| Ja'Quan McMillian | CB | Den | N/A | **** | ||
| Kyle Dugger | S | NE | 29 | **** | Questionable | Ankle |
| Derwin James | S | LAC | 28 | **** |