| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jayden Daniels | QB |
|
25 | No More Bye | ||
| Jared Goff | QB |
|
32 | No More Bye | ||
| Travis Etienne | RB |
|
27 | No More Bye | NFI | Hamstring |
| Derrick Henry | RB |
|
32 | Week 13 | ||
| Emmett Johnson | RB |
|
23 | No More Bye | ||
| Tony Pollard | RB |
|
29 | No More Bye | ||
| Elic Ayomanor | WR |
|
23 | No More Bye | ||
| Kendrick Bourne | WR |
|
31 | Week 14 | NFI | Lower leg |
| Mike Evans | WR |
|
33 | No More Bye | Questionable | Achilles |
| Zay Flowers | WR |
|
26 | Week 13 | ||
| Chris Godwin | WR |
|
30 | Week 10 | ||
| Demarcus Robinson | WR |
|
32 | No More Bye | ||
| Rashid Shaheed | WR |
|
28 | Week 11 | Questionable | Knee |
| Amon-Ra St. Brown | WR |
|
27 | No More Bye | ||
| Kyle Pitts | TE |
|
26 | Week 11 | ||
| Dalton Schultz | TE |
|
30 | No More Bye | ||
| Evan McPherson | PK |
|
27 | No More Bye | ||
| Nick Bosa | DL |
|
29 | No More Bye | ||
| Myles Garrett | DL |
|
30 | Week 11 | ||
| Trey Hendrickson | DL |
|
31 | Week 13 | ||
| Jarrian Jones | DL |
|
25 | No More Bye | ||
| George Karlaftis | DL |
|
25 | No More Bye | ||
| Kwity Paye | DL |
|
27 | Week 13 | ||
| Jaelan Phillips | DL |
|
28 | No More Bye | Questionable | Hamstring |
| Zack Baun | LB |
|
29 | Week 10 | Questionable | Back |
| T.J. Edwards | LB |
|
30 | Week 10 | ||
| Dre Greenlaw | LB |
|
29 | No More Bye | ||
| Nate Landman | LB |
|
27 | Week 11 | ||
| DeMarvion Overshown | LB |
|
26 | Week 14 | Questionable | Hamstring |
| Pete Werner | LB |
|
27 | No More Bye | ||
| Byron Murphy | CB |
|
28 | No More Bye | ||
| Dane Belton | S |
|
N/A | Week 13 | ||
| Nick Cross | S |
|
N/A | No More Bye |