| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Baker Mayfield | QB |
|
31 | Week 10 | ||
| Brock Purdy | QB |
|
26 | No More Bye | ||
| Blake Corum | RB |
|
25 | Week 11 | ||
| Woody Marks | RB |
|
25 | No More Bye | ||
| Kendre Miller | RB |
|
24 | No More Bye | ||
| David Montgomery | RB |
|
29 | No More Bye | Questionable | Groin |
| Dylan Sampson | RB |
|
22 | Week 11 | ||
| Rhamondre Stevenson | RB |
|
28 | Week 11 | Questionable | Knee |
| Jaylen Warren | RB |
|
28 | No More Bye | ||
| Javonte Williams | RB |
|
26 | Week 14 | ||
| Davante Adams | WR |
|
33 | Week 11 | NFI | Hamstring |
| Nico Collins | WR |
|
27 | No More Bye | ||
| KC Concepcion | WR |
|
22 | Week 11 | ||
| Stefon Diggs | WR |
|
32 | No More Bye | ||
| Tre Harris | WR |
|
24 | No More Bye | ||
| Puka Nacua | WR |
|
25 | Week 11 | Doubtful | Knee |
| Jaylen Waddle | WR |
|
27 | Week 10 | Questionable | Concussion |
| Hunter Henry | TE |
|
31 | Week 11 | ||
| Juwan Johnson | TE |
|
30 | No More Bye | ||
| Tucker Kraft | TE |
|
N/A | Week 11 | ||
| Spencer Shrader | PK |
|
27 | Week 13 | ||
| Abdul Carter | DL |
|
22 | No More Bye | Questionable | Knee |
| Mason Graham | DL |
|
23 | Week 11 | ||
| Khalil Mack | DL |
|
35 | No More Bye | ||
| Micah Parsons | DL |
|
28 | Week 11 | PUP | Knee - ACL |
| Quinnen Williams | DL |
|
28 | Week 14 | ||
| Isaiah McDuffie | LB |
|
27 | Week 11 | ||
| Bobby Okereke | LB |
|
30 | No More Bye | Questionable | Foot |
| Sonny Styles | LB |
|
21 | No More Bye | ||
| Josiah Trotter | LB |
|
21 | Week 10 | ||
| Keisean Nixon | CB |
|
N/A | Week 11 | ||
| Devon Witherspoon | CB |
|
25 | Week 11 | ||
| Nick Emmanwori | S |
|
22 | Week 11 |