| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| Lamar Jackson | QB | Bal | 28 | **** | ||
| Tony Pollard | RB | Ten | 28 | **** | ||
| Kimani Vidal | RB | LAC | 23 | **** | ||
| D'Andre Swift | RB | Chi | 26 | **** | ||
| Rachaad White | RB | TB | 26 | **** | ||
| Brian Robinson | RB | Was | 26 | **** | ||
| Jahmyr Gibbs | RB | Det | 23 | **** | ||
| Keenan Allen | WR | Chi | 33 | **** | ||
| Tyler Lockett | WR | Sea | 32 | **** | ||
| Darius Slayton | WR | NYG | 28 | **** | ||
| Tee Higgins | WR | Cin | 26 | **** | ||
| Allen Lazard | WR | NYJ | 29 | **** | ||
| D.K. Metcalf | WR | Pit | 27 | **** | ||
| Calvin Ridley | WR | Ten | 30 | **** | ||
| David Njoku | TE | Cle | 28 | **** | Questionable | Knee |
| Cole Kmet | TE | Chi | 26 | **** | ||
| Younghoe Koo | PK | Atl | 30 | **** | Questionable | Hip |
| Jason Sanders | PK | Mia | 29 | **** | ||
| Harold Landry | DL | Ten | 28 | **** | ||
| Khalil Mack | DL | LAC | 34 | **** | ||
| D.J. Wonnum | DL | Car | 27 | **** | ||
| Byron Young | DL | LAR | 27 | **** | ||
| Brenton Cox | LB | GB | N/A | **** | ||
| Ernest Jones | LB | Sea | 25 | **** | Questionable | Knee |
| Micah McFadden | LB | NYG | 25 | **** | Questionable | Neck |
| Eric Kendricks | LB | Dal | 33 | **** | ||
| Germaine Pratt | LB | Cin | 28 | **** | ||
| Tarheeb Still | CB | LAC | 22 | **** | ||
| Zyon McCollum | CB | TB | N/A | **** | ||
| Grant Delpit | S | Cle | 26 | **** | ||
| Brandon Jones | S | Den | 27 | **** | ||
| Marte Mapu | S | NE | N/A | **** | Questionable | Neck |