| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| J.J. McCarthy | QB | Min | 22 | **** | ||
| Bo Nix | QB | Den | 25 | **** | ||
| Sam Darnold | QB | Sea | 27 | **** | ||
| Justin Herbert | QB | LAC | 27 | **** | ||
| Tony Pollard | RB | Ten | 28 | **** | ||
| Rico Dowdle | RB | Car | 26 | **** | ||
| Tyrone Tracy Jr. | RB | NYG | 25 | **** | ||
| Braelon Allen | RB | NYJ | 21 | **** | ||
| James Cook | RB | Buf | 25 | **** | ||
| Sincere McCormick | RB | LV | N/A | **** | ||
| Bijan Robinson | RB | Atl | 23 | **** | ||
| Chase Brown | RB | Cin | 25 | **** | Questionable | Ankle |
| Puka Nacua | WR | LAR | 23 | **** | ||
| Zay Flowers | WR | Bal | 24 | **** | Questionable | Knee |
| Nico Collins | WR | Hou | 26 | **** | ||
| Ricky Pearsall | WR | SF | 24 | **** | ||
| Keenan Allen | WR | Chi | 33 | **** | ||
| Xavier Worthy | WR | KC | 22 | **** | ||
| Kyle Pitts | TE | Atl | 24 | **** | ||
| Isaiah Likely | TE | Bal | 25 | **** | ||
| Dalton Kincaid | TE | Buf | 26 | **** | ||
| Brenton Strange | TE | Jac | N/A | **** | ||
| Wil Lutz | PK | Den | 30 | **** | ||
| D.J. Wonnum | DL | Car | 27 | **** | ||
| Jared Verse | DL | LAR | 24 | **** | ||
| Nick Bosa | DL | SF | 27 | **** | ||
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| Leonard Williams | DL | Sea | 30 | **** | ||
| E.J. Speed | LB | Ind | 29 | **** | ||
| Patrick Queen | LB | Pit | 25 | **** | ||
| Akeem Davis-Gaither | LB | Cin | N/A | **** | ||
| Devin Lloyd | LB | Jac | 26 | **** | ||
| Brian Branch | S | Det | 23 | **** |