| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Derek Carr | QB | NO | 34 | **** | Questionable | Shoulder |
| Dak Prescott | QB | Dal | 31 | **** | Questionable | Hamstring |
| Cooper Rush | QB | Dal | N/A | **** | ||
| Matthew Stafford | QB | LAR | 37 | **** | ||
| Antonio Gibson | RB | NE | 26 | **** | ||
| Devin Singletary | RB | NYG | 27 | **** | ||
| Alvin Kamara | RB | NO | 29 | **** | Questionable | Groin |
| James Conner | RB | Ari | 29 | **** | Questionable | Knee |
| Ameer Abdullah | RB | LV | 31 | **** | ||
| Jonathon Brooks | RB | Car | 21 | **** | Questionable | Knee - ACL |
| A.J. Brown | WR | Phi | 27 | **** | ||
| Darnell Mooney | WR | Atl | 27 | **** | Questionable | Shoulder |
| Jauan Jennings | WR | SF | N/A | **** | ||
| Nick Westbrook-Ikhine | WR | Mia | 28 | **** | ||
| CeeDee Lamb | WR | Dal | 26 | **** | ||
| Justin Jefferson | WR | Min | 26 | **** | ||
| Chris Olave | WR | NO | 24 | **** | Questionable | Concussion |
| Cole Kmet | TE | Chi | 26 | **** | ||
| Kyle Pitts | TE | Atl | 24 | **** | ||
| Tyler Conklin | TE | LAC | 29 | **** | ||
| Austin Seibert | PK | Was | 28 | **** | ||
| Chris Boswell | PK | Pit | 34 | **** | ||
| Jared Verse | DL | LAR | 24 | **** | ||
| Emmanuel Ogbah | DL | Mia | 31 | **** | ||
| A'Shawn Robinson | DL | Car | 30 | **** | Questionable | Calf |
| Jonathon Cooper | DL | Den | 27 | **** | ||
| Nick Bolton | LB | KC | 25 | **** | ||
| Pete Werner | LB | NO | 25 | **** | Questionable | Concussion |
| E.J. Speed | LB | Ind | 29 | **** | ||
| Roquan Smith | LB | Bal | 28 | **** | ||
| Fred Warner | LB | SF | 28 | **** | ||
| Byron Murphy | CB | Min | 27 | **** | ||
| Nick Cross | S | Ind | N/A | **** |