| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| Baker Mayfield | QB | TB | 30 | **** | ||
| Will Levis | QB | Ten | 25 | **** | ||
| Jonathan Taylor | RB | Ind | 26 | **** | ||
| Zach Charbonnet | RB | Sea | 24 | **** | ||
| Tyrone Tracy Jr. | RB | NYG | 25 | **** | ||
| Tony Pollard | RB | Ten | 28 | **** | ||
| Jerry Jeudy | WR | Cle | 26 | **** | ||
| Terry McLaurin | WR | Was | 28 | **** | ||
| D.J. Moore | WR | Chi | 28 | **** | ||
| Tre Tucker | WR | LV | N/A | **** | ||
| George Pickens | WR | Pit | 23 | **** | ||
| Romeo Doubs | WR | GB | 25 | **** | Questionable | Concussion |
| Brenton Strange | TE | Jac | N/A | **** | ||
| David Njoku | TE | Cle | 28 | **** | Questionable | Knee |
| Dallas Goedert | TE | Phi | 30 | **** | ||
| Ka'imi Fairbairn | PK | Hou | 31 | **** | ||
| Braden Fiske | DL | LAR | 25 | **** | Questionable | Knee |
| A'Shawn Robinson | DL | Car | 30 | **** | Questionable | Calf |
| Harold Landry | DL | Ten | 28 | **** | ||
| Derick Hall | DL | Sea | 24 | **** | ||
| Keion White | DL | NE | N/A | **** | ||
| Nate Landman | LB | Atl | 26 | **** | ||
| Christian Harris | LB | Hou | N/A | **** | ||
| Ernest Jones | LB | Sea | 25 | **** | Questionable | Knee |
| Quincy Williams | LB | NYJ | 28 | **** | ||
| Cedric Gray | LB | Ten | 22 | **** | ||
| Roquan Smith | LB | Bal | 28 | **** | ||
| Devon Witherspoon | CB | Sea | 24 | **** | ||
| Alontae Taylor | CB | NO | N/A | **** | ||
| Camryn Bynum | S | Min | 26 | **** | ||
| Julian Love | S | Sea | 27 | **** |