| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jared Goff | QB | Det | 30 | **** | ||
| Justin Herbert | QB | LAC | 27 | **** | ||
| Mike Boone | RB | Car | N/A | **** | ||
| Alexander Mattison | RB | Mia | 26 | **** | ||
| Nick Chubb | RB | Cle | 29 | **** | ||
| Kimani Vidal | RB | LAC | 23 | **** | ||
| Ameer Abdullah | RB | LV | 31 | **** | ||
| Kendre Miller | RB | NO | 22 | **** | Questionable | Concussion |
| De'Von Achane | RB | Mia | 23 | **** | ||
| Sean Tucker | RB | TB | N/A | **** | ||
| Tank Dell | WR | Hou | 25 | **** | Questionable | Knee - ACL + MCL |
| Dontayvion Wicks | WR | GB | 23 | **** | ||
| Ja'Marr Chase | WR | Cin | 25 | **** | ||
| Nico Collins | WR | Hou | 26 | **** | ||
| George Pickens | WR | Pit | 23 | **** | ||
| JuJu Smith-Schuster | WR | KC | 28 | **** | ||
| A.J. Brown | WR | Phi | 27 | **** | ||
| Tee Higgins | WR | Cin | 26 | **** | ||
| Brock Bowers | TE | LV | 22 | **** | ||
| Will Reichard | PK | Min | 24 | **** | ||
| Chop Robinson | DL | Mia | 22 | **** | ||
| Josh Sweat | DL | Ari | 28 | **** | ||
| Alex Highsmith | DL | Pit | 27 | **** | ||
| Zach Allen | DL | Den | 27 | **** | ||
| Blake Cashman | LB | Min | 28 | **** | ||
| Akeem Davis-Gaither | LB | Cin | N/A | **** | ||
| Christian Rozeboom | LB | LAR | N/A | **** | ||
| Zaire Franklin | LB | Ind | 28 | **** | ||
| Daiyan Henley | LB | LAC | N/A | **** | Questionable | Shoulder - Labrum |
| DaRon Bland | CB | Dal | 25 | **** | ||
| Kenny Moore | CB | Ind | 29 | **** | ||
| Nick Cross | S | Ind | N/A | **** | ||
| Dane Belton | S | NYG | N/A | **** |