| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jared Goff | QB | Det | 30 | **** | ||
| Justin Herbert | QB | LAC | 27 | **** | ||
| Isaac Guerendo | RB | SF | 24 | **** | Questionable | Knee - MCL |
| Ray Davis | RB | Buf | 25 | **** | ||
| MarShawn Lloyd | RB | GB | 24 | **** | Questionable | Hamstring |
| Breece Hall | RB | NYJ | 23 | **** | ||
| Dameon Pierce | RB | Hou | 25 | **** | ||
| Bijan Robinson | RB | Atl | 23 | **** | ||
| Jahmyr Gibbs | RB | Det | 23 | **** | ||
| Kendre Miller | RB | NO | 22 | **** | Questionable | Concussion |
| De'Von Achane | RB | Mia | 23 | **** | ||
| Dontayvion Wicks | WR | GB | 23 | **** | ||
| Ja'Marr Chase | WR | Cin | 25 | **** | ||
| Tyreek Hill | WR | Mia | 31 | **** | Questionable | Wrist |
| A.J. Brown | WR | Phi | 27 | **** | ||
| Justin Jefferson | WR | Min | 26 | **** | ||
| T.J. Hockenson | TE | Min | 27 | **** | ||
| David Njoku | TE | Cle | 28 | **** | Questionable | Knee |
| Chig Okonkwo | TE | Ten | 26 | **** | ||
| Tyler Bass | PK | Buf | 28 | **** | ||
| Will Reichard | PK | Min | 24 | **** | ||
| Zach Sieler | DL | Mia | 29 | **** | ||
| Zach Allen | DL | Den | 27 | **** | ||
| Jonathan Greenard | DL | Min | 27 | **** | ||
| Travon Walker | DL | Jac | 24 | **** | ||
| Jamien Sherwood | LB | NYJ | 25 | **** | ||
| Akeem Davis-Gaither | LB | Cin | N/A | **** | ||
| Zack Baun | LB | Phi | 28 | **** | ||
| Blake Cashman | LB | Min | 28 | **** | ||
| Tarheeb Still | CB | LAC | 22 | **** | ||
| Deommodore Lenoir | CB | SF | 25 | **** | Questionable | Shoulder |
| Dane Belton | S | NYG | N/A | **** | ||
| Nick Cross | S | Ind | N/A | **** |