| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Derek Carr | QB | NO | 34 | **** | Questionable | Shoulder |
| Jalen Hurts | QB | Phi | 26 | **** | ||
| Antonio Gibson | RB | NE | 26 | **** | ||
| Chuba Hubbard | RB | Car | 25 | **** | ||
| James Cook | RB | Buf | 25 | **** | ||
| Ezekiel Elliott | RB | Dal | 29 | **** | ||
| Jonathan Taylor | RB | Ind | 26 | **** | ||
| Calvin Ridley | WR | Ten | 30 | **** | ||
| Cooper Kupp | WR | Sea | 31 | **** | ||
| Tyler Lockett | WR | Sea | 32 | **** | ||
| Ja'Lynn Polk | WR | NE | 23 | **** | Questionable | Shoulder |
| Ladd McConkey | WR | LAC | 23 | **** | ||
| Mike Evans | WR | TB | 31 | **** | ||
| Tank Dell | WR | Hou | 25 | **** | Questionable | Knee - ACL + MCL |
| Demario Douglas | WR | NE | 24 | **** | ||
| George Kittle | TE | SF | 31 | **** | ||
| Cole Kmet | TE | Chi | 26 | **** | ||
| Austin Seibert | PK | Was | 28 | **** | ||
| Cameron Dicker | PK | LAC | 24 | **** | ||
| Kwity Paye | DL | Ind | 26 | **** | ||
| Dexter Lawrence | DL | NYG | 27 | **** | Questionable | Elbow |
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| Leonard Williams | DL | Sea | 30 | **** | ||
| Joey Bosa | DL | Buf | 29 | **** | ||
| Jahlani Tavai | LB | NE | 28 | **** | ||
| Robert Spillane | LB | LV | 29 | **** | ||
| Azeez Al-Shaair | LB | Hou | 27 | **** | Questionable | Knee |
| Logan Wilson | LB | Cin | 28 | **** | Questionable | Knee |
| Ventrell Miller | LB | Jac | N/A | **** | ||
| Christian Gonzalez | CB | NE | N/A | **** | Questionable | Concussion |
| Rasul Douglas | CB | Buf | 29 | **** | ||
| Quentin Lake | S | LAR | N/A | **** | ||
| Jaquan Brisker | S | Chi | 26 | **** | Questionable | Concussion |