| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| Cooper Rush | QB | Dal | N/A | **** | ||
| Trevor Lawrence | QB | Jac | 25 | **** | Questionable | Shoulder - AC Joint |
| Anthony Richardson | QB | Ind | 22 | **** | Questionable | Back |
| Jaylen Warren | RB | Pit | 26 | **** | ||
| Sincere McCormick | RB | LV | N/A | **** | ||
| Jaleel McLaughlin | RB | Den | 24 | **** | ||
| Trey Benson | RB | Ari | 22 | **** | Questionable | Ankle |
| Isaiah Davis | RB | NYJ | 23 | **** | ||
| Ameer Abdullah | RB | LV | 31 | **** | ||
| Stefon Diggs | WR | NE | 31 | **** | Questionable | Knee - ACL |
| Marvin Harrison Jr. | WR | Ari | 22 | **** | ||
| Rome Odunze | WR | Chi | 22 | **** | ||
| Jalen Coker | WR | Car | 23 | **** | ||
| Troy Franklin | WR | Den | 22 | **** | ||
| Chris Godwin | WR | TB | 29 | **** | Questionable | Ankle |
| Jaxon Smith-Njigba | WR | Sea | 23 | **** | ||
| Elijah Moore | WR | Cle | 25 | **** | ||
| Jerry Jeudy | WR | Cle | 26 | **** | ||
| George Pickens | WR | Pit | 23 | **** | ||
| Pat Freiermuth | TE | Pit | 26 | **** | ||
| Taysom Hill | TE | NO | 34 | **** | Questionable | Knee - ACL |
| Hunter Henry | TE | NE | 30 | **** | Questionable | Foot |
| Wil Lutz | PK | Den | 30 | **** | ||
| Chris Jones | DL | KC | 30 | **** | ||
| Boye Mafe | DL | Sea | 26 | **** | ||
| Luke Gifford | LB | Ten | N/A | **** | ||
| Jordyn Brooks | LB | Mia | 27 | **** | Questionable | Wrist |
| Marist Liufau | LB | Dal | 24 | **** | ||
| Eric Kendricks | LB | Dal | 33 | **** | ||
| Devon Witherspoon | CB | Sea | 24 | **** | ||
| Brian Branch | S | Det | 23 | **** | ||
| Derwin James | S | LAC | 28 | **** |