| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Drake Maye | QB | NE | 22 | **** | ||
| Jayden Daniels | QB | Was | 24 | **** | ||
| Cooper Rush | QB | Dal | N/A | **** | ||
| Justin Herbert | QB | LAC | 27 | **** | ||
| Tom Brady | QB | F/A | 47 | **** | ||
| Tank Bigsby | RB | Jac | 23 | **** | ||
| Roschon Johnson | RB | Chi | 24 | **** | ||
| Israel Abanikanda | RB | SF | 22 | **** | ||
| Emanuel Wilson | RB | GB | 25 | **** | ||
| Michael Carter | RB | Ari | 25 | **** | ||
| Elijah Mitchell | RB | KC | 27 | **** | ||
| Khalil Herbert | RB | Ind | 27 | **** | ||
| Dameon Pierce | RB | Hou | 25 | **** | ||
| De'Von Achane | RB | Mia | 23 | **** | ||
| Zack Moss | RB | Cin | 27 | **** | Questionable | Neck |
| Nick Chubb | RB | Cle | 29 | **** | ||
| Raheem Mostert | RB | LV | 33 | **** | ||
| Kareem Hunt | RB | KC | 29 | **** | ||
| Aaron Jones | RB | Min | 30 | **** | ||
| Austin Ekeler | RB | Was | 29 | **** | ||
| Tyreek Hill | WR | Mia | 31 | **** | Questionable | Wrist |
| D.J. Moore | WR | Chi | 28 | **** | ||
| Romeo Doubs | WR | GB | 25 | **** | Questionable | Concussion |
| Tank Dell | WR | Hou | 25 | **** | Questionable | Knee - ACL + MCL |
| Jameson Williams | WR | Det | 24 | **** | ||
| Hunter Henry | TE | NE | 30 | **** | Questionable | Foot |
| Tyler Bass | PK | Buf | 28 | **** | ||
| Nick Bosa | DL | SF | 27 | **** | ||
| Chop Robinson | DL | Mia | 22 | **** | ||
| Travon Walker | DL | Jac | 24 | **** | ||
| Daiyan Henley | LB | LAC | N/A | **** | Questionable | Shoulder - Labrum |
| Blake Cashman | LB | Min | 28 | **** | ||
| E.J. Speed | LB | Ind | 29 | **** |