| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jared Goff | QB | Det | 30 | **** | ||
| C.J. Stroud | QB | Hou | 23 | **** | ||
| D'Andre Swift | RB | Chi | 26 | **** | ||
| Antonio Gibson | RB | NE | 26 | **** | ||
| Breece Hall | RB | NYJ | 23 | **** | ||
| Jaleel McLaughlin | RB | Den | 24 | **** | ||
| Joe Mixon | RB | Hou | 28 | **** | ||
| Braelon Allen | RB | NYJ | 21 | **** | ||
| Saquon Barkley | RB | Phi | 28 | **** | ||
| A.J. Brown | WR | Phi | 27 | **** | ||
| Brian Thomas Jr. | WR | Jac | 22 | **** | ||
| Ricky Pearsall | WR | SF | 24 | **** | ||
| Chris Godwin | WR | TB | 29 | **** | Questionable | Ankle |
| Troy Franklin | WR | Den | 22 | **** | ||
| Wan'Dale Robinson | WR | NYG | 24 | **** | ||
| Zay Flowers | WR | Bal | 24 | **** | Questionable | Knee |
| Sam LaPorta | TE | Det | 24 | **** | ||
| Jonnu Smith | TE | Mia | 29 | **** | ||
| Cairo Santos | PK | Chi | 33 | **** | ||
| Zach Sieler | DL | Mia | 29 | **** | ||
| Quinnen Williams | DL | NYJ | 27 | **** | Questionable | Hamstring |
| Dexter Lawrence | DL | NYG | 27 | **** | Questionable | Elbow |
| Trey Hendrickson | DL | Cin | 30 | **** | ||
| Jonathan Greenard | DL | Min | 27 | **** | ||
| Nakobe Dean | LB | Phi | 24 | **** | Questionable | Knee |
| Demario Davis | LB | NO | 36 | **** | ||
| Germaine Pratt | LB | Cin | 28 | **** | ||
| T.J. Edwards | LB | Chi | 28 | **** | ||
| Jordan Hicks | LB | Cle | 32 | **** | Questionable | Concussion |
| Charvarius Ward | CB | SF | 28 | **** | ||
| Tyrique Stevenson | CB | Chi | 24 | **** | ||
| Kyle Hamilton | S | Bal | 24 | **** | ||
| Johnathan Abram | S | NO | 28 | **** |