| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jameis Winston | QB | NYG | 31 | **** | ||
| Deshaun Watson | QB | Cle | 29 | **** | Questionable | Achilles |
| Kyler Murray | QB | Ari | 27 | **** | ||
| Austin Ekeler | RB | Was | 29 | **** | ||
| Nick Chubb | RB | Cle | 29 | **** | ||
| Joe Mixon | RB | Hou | 28 | **** | ||
| Jaylen Wright | RB | Mia | 22 | **** | ||
| Tyrone Tracy Jr. | RB | NYG | 25 | **** | ||
| Zamir White | RB | LV | 25 | **** | ||
| Kyren Williams | RB | LAR | 24 | **** | ||
| Emanuel Wilson | RB | GB | 25 | **** | ||
| Andrei Iosivas | WR | Cin | 25 | **** | ||
| Jordan Addison | WR | Min | 23 | **** | ||
| Josh Downs | WR | Ind | 23 | **** | ||
| Jaylen Waddle | WR | Mia | 26 | **** | ||
| Josh Palmer | WR | Buf | 25 | **** | ||
| Tre Tucker | WR | LV | N/A | **** | ||
| Keenan Allen | WR | Chi | 33 | **** | ||
| Deebo Samuel | WR | SF | 29 | **** | ||
| Tee Higgins | WR | Cin | 26 | **** | ||
| Zach Ertz | TE | Was | 34 | **** | ||
| George Kittle | TE | SF | 31 | **** | ||
| Evan Engram | TE | Den | 30 | **** | Questionable | Shoulder - Labrum |
| Harold Landry | DL | Ten | 28 | **** | ||
| Travon Walker | DL | Jac | 24 | **** | ||
| Kobie Turner | DL | LAR | N/A | **** | ||
| Nick Herbig | LB | Pit | N/A | **** | ||
| Josey Jewell | LB | Car | 30 | **** | Questionable | Concussion |
| Roquan Smith | LB | Bal | 28 | **** | ||
| Quincy Williams | LB | NYJ | 28 | **** | ||
| Payton Wilson | LB | Pit | 25 | **** | ||
| Jaylon Jones | CB | Ind | N/A | **** | ||
| Xavier McKinney | S | GB | 36 | **** |