| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Baker Mayfield | QB | TB | 30 | **** | ||
| Sam Darnold | QB | Sea | 27 | **** | ||
| Brock Purdy | QB | SF | 25 | **** | ||
| Patrick Taylor | RB | SF | 27 | **** | ||
| Kendre Miller | RB | NO | 22 | **** | Questionable | Concussion |
| Tony Pollard | RB | Ten | 28 | **** | ||
| Javonte Williams | RB | Dal | 25 | **** | ||
| Amon-Ra St. Brown | WR | Det | 25 | **** | ||
| Justin Jefferson | WR | Min | 26 | **** | ||
| Ricky Pearsall | WR | SF | 24 | **** | ||
| Adam Thielen | WR | Car | 34 | **** | ||
| Amari Cooper | WR | Buf | 30 | **** | ||
| Puka Nacua | WR | LAR | 23 | **** | ||
| Nick Westbrook-Ikhine | WR | Mia | 28 | **** | ||
| Jameson Williams | WR | Det | 24 | **** | ||
| Isaiah Likely | TE | Bal | 25 | **** | ||
| Tucker Kraft | TE | GB | N/A | **** | ||
| Sam LaPorta | TE | Det | 24 | **** | ||
| Justin Tucker | PK | Bal | 35 | **** | ||
| Jeffery Simmons | DL | Ten | 27 | **** | ||
| Maxx Crosby | DL | LV | 27 | **** | Questionable | Ankle |
| Jonathon Cooper | DL | Den | 27 | **** | ||
| Aidan Hutchinson | DL | Det | 24 | **** | Questionable | Lower leg |
| Tuli Tuipulotu | DL | LAC | 22 | **** | ||
| Logan Wilson | LB | Cin | 28 | **** | Questionable | Knee |
| Micah McFadden | LB | NYG | 25 | **** | Questionable | Neck |
| Nate Landman | LB | Atl | 26 | **** | ||
| Troy Andersen | LB | Atl | 26 | **** | Questionable | Knee |
| Fred Warner | LB | SF | 28 | **** | ||
| DaRon Bland | CB | Dal | 25 | **** | ||
| Chamarri Conner | CB | KC | N/A | **** | ||
| Antoine Winfield | S | TB | 26 | **** | ||
| Jeremy Chinn | S | Was | 27 | **** |