| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Jared Goff | QB | Det | 30 | **** | ||
| Baker Mayfield | QB | TB | 30 | **** | ||
| Jordan Love | QB | GB | 26 | **** | ||
| Ezekiel Elliott | RB | Dal | 29 | **** | ||
| Aaron Jones | RB | Min | 30 | **** | ||
| Austin Ekeler | RB | Was | 29 | **** | ||
| Javonte Williams | RB | Dal | 25 | **** | ||
| Ty Chandler | RB | Min | 26 | **** | ||
| Jaylen Warren | RB | Pit | 26 | **** | ||
| Wan'Dale Robinson | WR | NYG | 24 | **** | ||
| Alec Pierce | WR | Ind | 25 | **** | ||
| Chris Godwin | WR | TB | 29 | **** | Questionable | Ankle |
| Michael Pittman | WR | Ind | 27 | **** | ||
| Courtland Sutton | WR | Den | 29 | **** | ||
| Terry McLaurin | WR | Was | 28 | **** | ||
| Darius Slayton | WR | NYG | 28 | **** | ||
| David Njoku | TE | Cle | 28 | **** | Questionable | Knee |
| Cole Kmet | TE | Chi | 26 | **** | ||
| Cameron Dicker | PK | LAC | 24 | **** | ||
| Daniel Carlson | PK | LV | 30 | **** | ||
| A.J. Epenesa | DL | Buf | 26 | **** | ||
| Jonathon Cooper | DL | Den | 27 | **** | ||
| Boye Mafe | DL | Sea | 26 | **** | ||
| Maliek Collins | DL | SF | N/A | **** | ||
| Alex Anzalone | LB | Det | 30 | **** | ||
| Bobby Wagner | LB | Was | 34 | **** | ||
| Jerome Baker | LB | Ten | 28 | **** | ||
| Jordyn Brooks | LB | Mia | 27 | **** | Questionable | Wrist |
| Patrick Queen | LB | Pit | 25 | **** | ||
| Jack Campbell | LB | Det | 24 | **** | ||
| Jaylon Jones | CB | Ind | N/A | **** | ||
| Brian Branch | S | Det | 23 | **** | ||
| Xavier McKinney | S | GB | 36 | **** |