| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Caleb Williams | QB | Chi | 23 | **** | Questionable | Wrist |
| C.J. Stroud | QB | Hou | 23 | **** | ||
| Will Levis | QB | Ten | 25 | **** | ||
| Jerome Ford | RB | Cle | 25 | **** | Questionable | Ankle |
| Tank Bigsby | RB | Jac | 23 | **** | ||
| Jaleel McLaughlin | RB | Den | 24 | **** | ||
| James Conner | RB | Ari | 29 | **** | Questionable | Knee |
| Tony Pollard | RB | Ten | 28 | **** | ||
| J.K. Dobbins | RB | LAC | 26 | **** | ||
| Jaylen Waddle | WR | Mia | 26 | **** | ||
| Diontae Johnson | WR | Hou | 28 | **** | ||
| Allen Lazard | WR | NYJ | 29 | **** | ||
| Xavier Legette | WR | Car | 24 | **** | Questionable | Foot |
| Adam Thielen | WR | Car | 34 | **** | ||
| Mike Evans | WR | TB | 31 | **** | ||
| Amari Cooper | WR | Buf | 30 | **** | ||
| Stefon Diggs | WR | NE | 31 | **** | Questionable | Knee - ACL |
| Jalen Nailor | WR | Min | N/A | **** | ||
| Tucker Kraft | TE | GB | N/A | **** | ||
| Evan Engram | TE | Den | 30 | **** | Questionable | Shoulder - Labrum |
| Dallas Goedert | TE | Phi | 30 | **** | ||
| Matthew Wright | PK | Ten | N/A | **** | ||
| Byron Young | DL | LAR | 27 | **** | ||
| Brian Burns | DL | NYG | 27 | **** | ||
| Andrew Van Ginkel | DL | Min | 29 | **** | ||
| Jonathan Greenard | DL | Min | 27 | **** | ||
| Troy Andersen | LB | Atl | 26 | **** | Questionable | Knee |
| Nakobe Dean | LB | Phi | 24 | **** | Questionable | Knee |
| Kyzir White | LB | Ari | 29 | **** | ||
| Jahlani Tavai | LB | NE | 28 | **** | ||
| Zyon McCollum | CB | TB | N/A | **** | ||
| Quentin Lake | S | LAR | N/A | **** | ||
| Jessie Bates | S | Atl | 28 | **** |