| Name | Pos | Team | Age | Bye Week | Health | Injury |
|---|---|---|---|---|---|---|
| Cooper Rush | QB | Dal | N/A | **** | ||
| Justin Herbert | QB | LAC | 27 | **** | ||
| Bryce Young | QB | Car | 23 | **** | ||
| Zach Charbonnet | RB | Sea | 24 | **** | ||
| Emanuel Wilson | RB | GB | 25 | **** | ||
| Michael Carter | RB | Ari | 25 | **** | ||
| Elijah Mitchell | RB | KC | 27 | **** | ||
| Khalil Herbert | RB | Ind | 27 | **** | ||
| Dameon Pierce | RB | Hou | 25 | **** | ||
| Devin Singletary | RB | NYG | 27 | **** | ||
| Aaron Jones | RB | Min | 30 | **** | ||
| Ray Davis | RB | Buf | 25 | **** | ||
| MarShawn Lloyd | RB | GB | 24 | **** | Questionable | Hamstring |
| Isaac Guerendo | RB | SF | 24 | **** | Questionable | Knee - MCL |
| Raheem Mostert | RB | LV | 33 | **** | ||
| Tyreek Hill | WR | Mia | 31 | **** | Questionable | Wrist |
| Xavier Worthy | WR | KC | 22 | **** | ||
| D.J. Moore | WR | Chi | 28 | **** | ||
| Ja'Marr Chase | WR | Cin | 25 | **** | ||
| Romeo Doubs | WR | GB | 25 | **** | Questionable | Concussion |
| Jameson Williams | WR | Det | 24 | **** | ||
| Dontayvion Wicks | WR | GB | 23 | **** | ||
| Sam LaPorta | TE | Det | 24 | **** | ||
| Jake Bates | PK | Det | 26 | **** | ||
| Montez Sweat | DL | Chi | 28 | **** | ||
| Chop Robinson | DL | Mia | 22 | **** | ||
| Myles Garrett | DL | Cle | 29 | **** | ||
| Tyrice Knight | LB | Sea | 24 | **** | ||
| Blake Cashman | LB | Min | 28 | **** | ||
| Daiyan Henley | LB | LAC | N/A | **** | Questionable | Shoulder - Labrum |
| Jamien Sherwood | LB | NYJ | 25 | **** | ||
| DaRon Bland | CB | Dal | 25 | **** | ||
| Dane Belton | S | NYG | N/A | **** |